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D5946

Sigma-Aldrich

PD 150606

≥97% (HPLC)

Synonym(s):

(2Z)-3-(4-iodophenyl)-2-mercapto-2-Propenoic acid, 3-(4-iodophenyl)-2-mercapto-(Z)-2-propenoic acid

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About This Item

Empirical Formula (Hill Notation):
C9H7IO2S
CAS Number:
179528-45-1
Molecular Weight:
306.12
MDL number:
MFCD00949076
UNSPSC Code:
12352200
PubChem Substance ID:
329798817
NACRES:
NA.77

Quality Level

100

Assay

≥97% (HPLC)

form

powder

storage condition

protect from light

color

yellowish

solubility

DMSO: >20 mg/mL

storage temp.

−20°C

SMILES string

OC(=O)\C(S)=C\c1ccc(I)cc1

InChI

1S/C9H7IO2S/c10-7-3-1-6(2-4-7)5-8(13)9(11)12/h1-5,13H,(H,11,12)/b8-5-

InChI key

DJCVSFWGKYHMKH-YVMONPNESA-N

Biochem/physiol Actions

PD 150606 is a selective; cell-permeable; non-peptide; uncompetitive calpain inhibitor.

Pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

Signal Word

Danger

Hazard Statements

H301,H315,H317,H318,H335

Hazard Classifications

Acute Tox. 3 Oral - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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ALLN Cell-permeable inhibitor of calpain I (Ki = 190 nM), calpain II (Ki = 220 nM), cathepsin B (Ki = 150 nM), and cathepsin L (Ki = 500 pM).

Sigma-Aldrich

208719

ALLN

Ac-YVAD-cmk ≥95% (HPLC)

Sigma-Aldrich

SML0429

Ac-YVAD-cmk

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