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C8037

Supelco

Clobetasol propionate

analytical standard

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About This Item

Empirical Formula (Hill Notation):
C25H32ClFO5
CAS Number:
Molecular Weight:
466.97
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

Assay

≥98%

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
veterinary

format

neat

storage temp.

2-8°C

SMILES string

CCC(=O)O[C@@]1([C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)CCl

InChI

1S/C25H32ClFO5/c1-5-21(31)32-25(20(30)13-26)14(2)10-18-17-7-6-15-11-16(28)8-9-22(15,3)24(17,27)19(29)12-23(18,25)4/h8-9,11,14,17-19,29H,5-7,10,12-13H2,1-4H3/t14-,17-,18-,19-,22-,23-,24-,25-/m0/s1

InChI key

CBGUOGMQLZIXBE-XGQKBEPLSA-N

Gene Information

human ... NR3C1(2908)
rat ... Nr3c1(24413)

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General description

Clobetasol propionate is a novel and highly potent, topical corticosteroid, which is being assessed for its utility in the treatment of bullous pemphigoid.
Clobetasol propionate is a novel and highly potent, topical corticosteroid, which is being assessed for its utility in the treatment of bullous pemphigoid.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Health hazard

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Chronic 4 - Repr. 1B - STOT RE 2

Target Organs

Adrenal gland,Immune system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number

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Open preliminary clinical trial of clobetasol propionate ointment in adhesive paste for treatment of chronic oral vesiculoerosive diseases
Lozada-Nur F, et al.
Oral Surgery, Oral Medicine, and Oral Pathology, 71, 283-287 (1991)
Open preliminary clinical trial of clobetasol propionate ointment in adhesive paste for treatment of chronic oral vesiculoerosive diseases.
Lozada-Nur F and Huang M Z
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 71(3), 283-287 (1991)
Treatment of bullous pemphigoid with topical clobetasol propionate
Westerhof W
Journal of the American Academy of Dermatology, 20, 458-461 (1989)
Treatment of bullous pemphigoid with topical clobetasol propionate.
Westerhof W.
Journal of the American Academy of Dermatology, 20(3), 458-461 (1989)
S R Wiegell et al.
The British journal of dermatology, 171(6), 1487-1492 (2014-07-26)
Photodynamic therapy (PDT) is an effective and established treatment for actinic keratoses (AK) and nonmelanoma skin cancer. The main side-effects of PDT are post-treatment erythema and oedema, and pain during illumination. Severe erythema after PDT enhances the down time associated

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