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Key Documents

B0301

Sigma-Aldrich

Biotin

meets USP testing specifications

Synonym(s):

D-Biotin, Bios II, Coenzyme R, Vitamin B7, Vitamin H

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500 MG
NOK 2,110.00
5 G
NOK 13,610.00
25 G
NOK 49,750.00

NOK 2,110.00


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500 MG
NOK 2,110.00
5 G
NOK 13,610.00
25 G
NOK 49,750.00

About This Item

Empirical Formula (Hill Notation):
C10H16N2O3S
CAS Number:
Molecular Weight:
244.31
Beilstein:
86838
EC Number:
MDL number:
UNSPSC Code:
12352201
eCl@ss:
34058011
PubChem Substance ID:
NACRES:
NA.21

NOK 2,110.00


Please contact Customer Service for Availability

Request a Bulk Order

biological source

synthetic (organic)

Quality Level

Agency

meets USP testing specifications

Assay

97.5-102.0%

form

powder

color

white

mp

231-233 °C (lit.)

application(s)

pharmaceutical (small molecule)

storage temp.

2-8°C

SMILES string

[H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2

InChI

1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1

InChI key

YBJHBAHKTGYVGT-ZKWXMUAHSA-N

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Application

<ul>
<li><strong>Protein Biotinylation Studies:</strong> Advanced strategies for biotinylation site characterization in proteins are being developed using biotin, improving the precision of protein modification techniques critical for biochemical research and drug development (Zhu, 2024).</li>
</ul>

Biochem/physiol Actions

Essential vitamin that is important for amino acid and energy metabolism, and fatty acid synthesis. It is a prosthetic group in four mammalian carboxylase families and facilitates the binding and transfer of carbon dioxide.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Tazu Aoki et al.
Neuron, 78(5), 881-894 (2013-05-21)
The encoding of long-term associative memories for learned behaviors is a fundamental brain function. Yet, how behavior is stably consolidated and retrieved in the vertebrate cortex is poorly understood. We trained zebrafish in aversive reinforcement learning and measured calcium signals
Tuan V Bui et al.
Neuron, 78(1), 191-204 (2013-04-16)
Accurate motor performance depends on the integration in spinal microcircuits of sensory feedback information. Hand grasp is a skilled motor behavior known to require cutaneous sensory feedback, but spinal microcircuits that process and relay this feedback to the motor system
Naruo Nikoh et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(28), 10257-10262 (2014-07-02)
Obligate insect-bacterium nutritional mutualism is among the most sophisticated forms of symbiosis, wherein the host and the symbiont are integrated into a coherent biological entity and unable to survive without the partnership. Originally, however, such obligate symbiotic bacteria must have
Stuart Trenholm et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(37), 14927-14938 (2013-09-13)
Recently, we demonstrated that gap junction coupling in the population of superior coding ON-OFF directionally selective ganglion cells (DSGCs) genetically labeled in the Hb9::eGFP mouse retina allows the passage of lateral anticipatory signals that help track moving stimuli. Here, we
Konstantinos Ampatzis et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(26), 10875-10886 (2013-06-28)
In vertebrates, spinal circuits drive rhythmic firing in motoneurons in the appropriate sequence to produce locomotor movements. These circuits become active early during development and mature gradually to acquire the flexibility necessary to accommodate the increased behavioral repertoire of adult

Articles

Importance and uses of biotin in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures

Questions

  1. Biotin (B0301) was left at room temp overnite, is it still good to use?

    1 answer
    1. This product is shipped at ambient temperature and is relatively stable for the short-term. Refrigerated products that ship at ambient temperature are allowed up to 2 weeks for transit time. Provided that the product was stored properly prior to being left out overnight, there should be no appreciable degradation. Prior to use, inspect the product for discoloration, changes in solubility, and cloudiness of solution. These may be signs that the product quality has been compromised.

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