901990
Tetrazine-acid
Synonym(s):
4-(1,2,4,5-Tetrazin-3-yl)benzeneacetic acid
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About This Item
Empirical Formula (Hill Notation):
C10H8N4O2
CAS Number:
Molecular Weight:
216.20
MDL number:
UNSPSC Code:
12352106
NACRES:
NA.22
Recommended Products
![3-(([1,1′-Biphenyl]-4-ylmethyl)thio)-6-methyl-1,2,4,5-tetrazine >98%](/deepweb/assets/sigmaaldrich/product/structures/641/985/7d39c434-c9ea-490e-974f-7653ca3b9e8c/640/7d39c434-c9ea-490e-974f-7653ca3b9e8c.png)
form
powder or crystals
availability
available only in USA
storage temp.
−20°C
Application
Tetrazine-acid demonstrates exceptionally fast cycloaddition kinetics with trans-cyclooctene (TCO) as the dienophile (up to 30,000 M-1 s-1). These have been the fastest kinetics reported for a bio orthogonal reaction. The chemical stability of tetrazines is substantially lower compared to methyltetrazines, thus requiring more careful selection of reagents and conditions for chemical transformation. However, tetrazine chemistry is still in an acceptable range for many applications.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Self-react. C
Storage Class Code
5.2 - Organic peroxides and self-reacting hazardous materials
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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