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69545

Supelco

Kaempferide

analytical standard

Synonym(s):

3,5,7-Trihydroxy-4′-methoxyflavone, KF, 4′-Methoxy-3,5,7-trihydroxyflavone

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About This Item

Empirical Formula (Hill Notation):
C16H12O6
CAS Number:
Molecular Weight:
300.26
Beilstein:
305378
EC Number:
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

Assay

≥99.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

COc1ccc(cc1)C2=C(O)C(=O)c3c(O)cc(O)cc3O2

InChI

1S/C16H12O6/c1-21-10-4-2-8(3-5-10)16-15(20)14(19)13-11(18)6-9(17)7-12(13)22-16/h2-7,17-18,20H,1H3

InChI key

SQFSKOYWJBQGKQ-UHFFFAOYSA-N

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General description

Kaempferide is a naturally occurring, O-methylated flavonol found in Kaempferia galanga. It exhibits a variety of pharmacological effects such as anti-inflammatory, anti-viral, anti-oxidant, anti-bacterial and antitumor properties.

Application

Kaempferide may be used as an analytical reference standard for the quantification of the analyte in propolis and traditional Chinese medicine Zuo Gui Wan using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

This compound is commonly found in plants of the genus: arnica silybum

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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A combined HPLC-PDA and HPLC-MS method for quantitative and qualitative analysis of 10 major constituents in the traditional Chinese medicine Zuo Gui Wan
Liang X, et al.
Journal of Pharmaceutical and Biomedical Analysis, 49(4), 931-936 (2009)
Kaempferide prevents titanium particle induced osteolysis by suppressing JNK activation during osteoclast formation
Jiao Z, et al.
Scientific Reports, 7(1) (2017)
Selective analysis of phenolic compounds in propolis by HPLC?MS/MS
Medana C, et al.
Phytochemical Analysis, 19(1), 32-39 (2008)
Ehab Ghazy et al.
European journal of medicinal chemistry, 200, 112338-112338 (2020-06-05)
Histone modifying proteins, specifically histone deacetylases (HDACs) and bromodomains, have emerged as novel promising targets for anticancer therapy. In the current work, based on available crystal structures and docking studies, we designed dual inhibitors of both HDAC6/8 and the bromodomain
Cuiping Zhang et al.
Journal of food science, 82(7), 1602-1607 (2017-06-01)
Brazilian green propolis is known as an appreciable natural antioxidant with abundant polyphenolic compounds. For quality control, a fingerprint-efficacy study of Brazilian green propolis was carried out in this work. Chemical fingerprints of Brazilian green propolis from 22 different sources

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