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(S)-ar-Turmerone

analytical standard

Synonym(s):

(S)-2-Methyl-6-(4-methylphenyl)-2-hepten-4-one

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About This Item

Empirical Formula (Hill Notation):
C15H20O
CAS Number:
Molecular Weight:
216.32
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:

grade

analytical standard

Assay

≥90.0% (GC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

C[C@@H](CC(=O)\C=C(\C)C)c1ccc(C)cc1

InChI

1S/C15H20O/c1-11(2)9-15(16)10-13(4)14-7-5-12(3)6-8-14/h5-9,13H,10H2,1-4H3/t13-/m0/s1

InChI key

NAAJVHHFAXWBOK-ZDUSSCGKSA-N

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General description

(S)-ar-Turmerone is the major constituent of turmeric oil derived from turmeric[1], which can find pharmaceutical applications due to its antibacterial, anti-carcinogenic, insect-repellent, anti-oxidant and anti-fungal properties.[2][1]

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Yue Aratanechemuge et al.
International journal of molecular medicine, 9(5), 481-484 (2002-04-17)
We have investigated the effects of ar-turmerone isolated from turmeric (Curcuma longa L) on DNA of human leukemia cell lines, Molt 4B, HL-60 and stomach cancer KATO III cells. It was found that selective induction of apoptosis by ar-turmerone was
Sun Young Park et al.
Neurochemistry international, 61(5), 767-777 (2012-07-07)
Despite data supporting an immune-modulating effect of ar-turmerone in vitro, the underlying signaling pathways are largely unknown. Here, we investigated the anti-neuroinflammatory properties of ar-turmerone in LPS-stimulated BV-2 microglial cells. Increased pro-inflammatory cytokines and chemokines, PGE(2), NO and ROS production
Sun Young Park et al.
International immunopharmacology, 14(1), 13-20 (2012-06-26)
Amyloid β (Aβ) induces the production of neuroinflammatory molecules, which may contribute to the pathogenesis of numerous neurodegenerative diseases. Therefore, suppression of neuroinflammatory molecules could be developed as a therapeutic method. Aromatic (ar)-turmerone, turmeric oil isolated from Curcuma longa, has
Grace G L Yue et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 48(8-9), 2011-2020 (2010-05-05)
The rhizome of Curcuma longa (CL) has been commonly used in Asia as a potential candidate for the treatment of different diseases, including inflammatory disorders and cancers. The present study evaluated the anti-proliferative activities of the isolated compounds (three curcuminoids
Yongkyu Lee
BMB reports, 42(2), 96-100 (2009-03-03)
Aromatic (ar)-turmerone from turmeric oil displays anti-tumorigenesis activity that includes inhibited cell proliferation. This study investigated ar-turmerone-mediated apoptotic protein activation in human lymphoma U937 cells. Ar-turmerone treatment inhibited U937 cell viability in a concentration-dependent fashion, with inhibition exceeding 84%. Moreover

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