03-0167-00

SMC^® Human IL-1α High Sensitivity Kit

1 kit sufficient for 96 wells, input: serum, plasma

• Synonym(s): IL-1 alpha Single Molecule Counting Kit, IL-1 alpha immunoassay kit, IL-1 alpha ultra-sensitive immunoassay, Interleukin-1 alpha immunoassay kit
• UNSPSC Code: 12161503
• NACRES: NA.84

Properties

• usage: kit sufficient for 96 wells
• species reactivity: human
• manufacturer/tradename: SMC^®
• assay range: sensitivity: 0.12 pg/mL; (lower limit of quantification); inter-assay cv: <20%; intra-assay cv: <15%; standard curve range: 0.06-60 pg/mL
• technique(s): ELISA: suitable; single molecule counting: suitable
• input: serum; plasma
• compatibility: for use with SMCxPRO^® and Erenna<TMSYMBOL></TMSYMBOL> (validated)
• shipped in: wet ice
• storage temp.: 2-8°C

Description

General description

The SMC^® human IL-1α High Sensitivity Immunoassay Kit contains all reagents required to perform the assay. This assay takes advantage of a standard immunoassay workflow configured in a standard plate format.

Assay protocols are similar to existing sandwich ELISA methods with two key differences:
1) Elution buffer disrupts the sandwich, separating the labeled detection antibody for quantification.
2)The Erenna and SMCxPRO^® immunoassay systems detect analytes using Single Molecule Counting (SMC^®) technology.

Specificity

Non-human primate plasma: 4 out of 4 individuals found to be detectable.
Canine plasma: 3 out of 4 individuals found to be detectable.
Rat plasma: 1 out of 4 individuals found to be detectable.
Although IL-1α was detectable, the assay has not been validated for these species.

Legal Information

SMC is a registered trademark of Singulex

SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H302 + H332,H311,H319,H360FD,H412
• Precautionary Statements: P273 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects