Skip to Content
Merck
All Photos(3)

Documents

850092P

Avanti

Brain Lyso PS

Avanti Research™ - A Croda Brand 850092P, powder

Synonym(s):

L-α-lysophosphatidylserine (Brain, Porcine) (sodium salt)

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

CAS Number:
383907-66-2
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (LPS; may contain up to 10% of the 2-LPS isomer, TLC)

form

powder

packaging

pkg of 1 × 10 mg (850092P-10mg)
pkg of 1 × 5 mg (850092P-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850092P

lipid type

phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)([H])COC(CCCCCCCCCCCCCCCCC)=O.[Na+]

General description

Lyso-phosphatidylserine (lyso-PS) is produced by the enzymatic action of phospholipase A1 and A2 on phosphatidylserine.

Application

Brain Lyso PS is suitable for use:
  • as standard to quantify lipids using ultra high performance liquid chromatography-electrospray ionization-tandem mass spectrometry (UHPLC-ESI-MS/MS)
  • in the preparation of liposomes for coating dynabeads for binding of factor H (fH)
  • as a ligand for G-protein coupled receptor 34 (GPR34) in in vitro experiments to investigate its effect granulosa cells(GC) and hormone production
  • as substrate for sicariid phospholipase D (PLD) toxins (SicTox) enzymes

Biochem/physiol Actions

Lyso-Phosphatidylserine (Lyso-PS) plays a key role in histamine release from mast cells. Lyso-PS inhibits the growth to T cells. It is a chemotactic substance for fibroblast and tumor cells. Lyso-PS is involved in tumor progression and allergic reactions.

Packaging

5 mL Amber Glass Screw Cap Vial (850092P-10mg)
5 mL Amber Glass Screw Cap Vial (850092P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 3

1 of 3

Brain PS Avanti Research™ - A Croda Brand

Avanti

840032P

Brain PS

Soy PS Avanti Research™ - A Croda Brand 870336C

Avanti

870336C

Soy PS

L-α-Lysophosphatidylcholine from egg yolk ≥99%, Type I, powder

Sigma-Aldrich

L4129

L-α-Lysophosphatidylcholine from egg yolk

Ultra-high-performance liquid chromatography electrospray ionization tandem mass spectrometry for accurate analysis of glycerophospholipids and sphingolipids in drug resistance tumor cells
Li L, et al.
Journal of Chromatography A, 1381(3), 140-148 (2015)
Annexin-II, DNA, and histones serve as factor H ligands on the surface of apoptotic cells
Leffler J, et al.
Test, 285(6), 3766-3776 (2010)
Lysophosphatidylserine stimulates chemotactic migration of colorectal cancer cells through GPR34 and PI3K/Akt pathway
Iida Y, et al.
Anticancer Research, 34(10), 5465-5472 (2014)
G protein-coupled receptor 34 in ovarian granulosa cells of cattle: changes during follicular development and potential functional implications
Spicer LJ, et al.
Domestic Animal Endocrinology, 59(6), 90-99 (2017)
Altered immune response in mice deficient for the G protein-coupled receptor GPR34
Liebscher I, et al.
Test, 286(3), 2101-2110 (2011)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service