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P5402

Sigma-Aldrich

Poly(ethylene glycol)

average mol wt 1,450

Synonym(s):

Polyethylene glycol, PEG

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About This Item

Linear Formula:
H(OCH2CH2)nOH
CAS Number:
MDL number:
UNSPSC Code:
12352104
PubChem Substance ID:
NACRES:
NA.22

form

powder, flakes, or chunks

mol wt

average mol wt 1,450

pH

4.5-7.5

viscosity

26.5 cSt (210 °F)

mp

43-46 °C

solubility

water: soluble (approximately 720 mg/ml, 20 °C)

density

1.0919 g/mL at 60 °C
1.0761 g/mL at 80 °C

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Application


  • Composite scaffolds for bone regeneration: A study describes the development of a composite scaffold incorporating polyethylene glycol, gellan gum, and hydroxyapatite, with added ginseng derived Compound K, indicating potential applications in bone regeneration (Thangavelu et al., 2024).

  • Enhanced wound healing: Research discusses AI-driven optimization of PCL/PEG electrospun scaffolds, highlighting their improved efficacy in in vivo wound healing applications (Virijević et al., 2024).

  • Catch and release cryogels: Redox-responsive cryogels made from polyethylene glycol, which can capture and release proteins and cells, suggesting their potential in biomedical applications (Calik et al., 2024).

  • Antibacterial hydrogels for wound dressing: A study presents light-degradable nanocomposite hydrogels containing polyethylene glycol, aimed at antibacterial wound dressing applications, demonstrating innovative uses in medical materials (Fang et al., 2024).

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Natalie Gavrilov-Yusim et al.
BMC biotechnology, 8, 3-3 (2008-01-16)
The isolation and production of human monoclonal antibodies is becoming an increasingly important pursuit as biopharmaceutical companies migrate their drug pipelines away from small organic molecules. As such, optimization of monoclonal antibody technologies is important, as this is becoming the
Benny Abraham Kaipparettu et al.
PloS one, 8(5), e61747-e61747 (2013-05-15)
Mitochondrial-nucleus cross talks and mitochondrial retrograde regulation can play a significant role in cellular properties. Transmitochondrial cybrid systems (cybrids) are an excellent tool to study specific effects of altered mitochondria under a defined nuclear background. The majority of the studies
Antonio Pantelias et al.
Cancers, 12(9) (2020-08-23)
For precision cancer radiotherapy, high linear energy transfer (LET) particle irradiation offers a substantial advantage over photon-based irradiation. In contrast to the sparse deposition of low-density energy by χ- or γ-rays, particle irradiation causes focal DNA damage through high-density energy
Corinne E Griguer et al.
PloS one, 3(11), e3655-e3655 (2008-11-06)
Mitochondria dysfunction and hypoxic microenvironment are hallmarks of cancer cell biology. Recently, many studies have focused on isolation of brain cancer stem cells using CD133 expression. In this study, we investigated whether CD133 expression is regulated by bioenergetic stresses affecting
Mark A Rice et al.
Acta biomaterialia, 5(1), 152-161 (2008-09-17)
Ultrasound has potential as a non-destructive analytical technique to provide real-time online assessments of matrix evolution in cell-hydrogel constructs used in tissue engineering. In these studies, chondrocytes were encapsulated in poly(ethylene glycol) hydrogels, and gel degradation was manipulated to provide

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