D106208

3,4-Dihydro-2H-pyran

97%

• Synonym(s): 2,3,4-Trihydropyran, 2H-3,4-Dihydropyran, Dihydro-2H-pyran, Dihydropyran
• Empirical Formula (Hill Notation): C₅H₈O
• CAS Number: 110-87-2
• Molecular Weight: 84.12
• Beilstein: 103493
• EC Number: 203-810-4
• MDL number: MFCD00006558
• UNSPSC Code: 12352005
• PubChem Substance ID: 24893341
• NACRES: NA.22

Properties

• vapor density: 2.9 (vs air)
• Quality Level: 200
• Assay: 97%
• form: liquid
• refractive index: n20/D 1.440 (lit.)
• bp: 86 °C (lit.)
• mp: −70 °C (lit.)
• density: 0.922 g/mL at 25 °C (lit.)
• SMILES string: C1COC=CC1
• InChI: 1S/C5H8O/c1-2-4-6-5-3-1/h2,4H,1,3,5H2
• InChI key: BUDQDWGNQVEFAC-UHFFFAOYSA-N

Description

Application

3,4-Dihydro-2H-pyran can be used as a reactant to synthesize:

• Tetrahydropyranylated product from alcohols in the presence of phenolsulfonic acid-formaldehyde resin catalyst.
• Tetrahydropyran derivatives by reacting pyrazoles in the presence of trifluoroacetic acid.
• 1,2,3,4-Tetrahydroquinoline derivatives by cation-exchange resin catalyzed Domino reaction with aromatic amines.
• Tetrahydroquinolines from aryl azides in the presence of FeCl₃-NaI.

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H315,H317,H319,H412
• Precautionary Statements: P210 - P233 - P273 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Aquatic Chronic 3 - Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - Skin Sens. 1B
• Supplementary Hazards: EUH019
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 5.0 °F - closed cup
• Flash Point(C): -15 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves