725897
2-(Chloromethyl)benzoyl chloride
≥96.0% (GC)
Synonym(s):
α-Chloro-o-toluoyl chloride
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About This Item
Empirical Formula (Hill Notation):
C8H6Cl2O
CAS Number:
Molecular Weight:
189.04
Beilstein:
1940781
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Assay
≥96.0% (GC)
96.0-104.0% (T)
form
liquid
functional group
acyl chloride
chloro
SMILES string
ClCc1ccccc1C(Cl)=O
InChI
1S/C8H6Cl2O/c9-5-6-3-1-2-4-7(6)8(10)11/h1-4H,5H2
InChI key
TXZFBHYDQGYOIT-UHFFFAOYSA-N
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Skin Corr. 1B
Storage Class Code
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Joo-Eun Kim et al.
Colloids and surfaces. B, Biointerfaces, 150, 362-372 (2016-11-09)
The purpose of this study was to develop hyaluronan-coated nanoemulsions (HNEs) with high solubilizing capacity and tumor cell targeting capability for the poorly soluble paclitaxel. The HNEs were composed of dl-a-tocopheryl acetate, soybean oil, polysorbate 80, and ferric chloride and
Song Yi Lee et al.
ACS applied materials & interfaces, 9(27), 22308-22320 (2017-06-18)
An amphiphilic hyaluronic acid-ceramide-dopamine (HACE-d) conjugate was prepared, and HACE-d-based nanoparticles (NPs) including phloretin (as an inhibitor of glucose transporter (GLUT1)) were fabricated. Mussel-inspired property of d was introduced to HACE NPs, and it may improve tumor targetability and penetration
Joo-Eun Kim et al.
International journal of nanomedicine, 12, 645-658 (2017-02-09)
Paclitaxel-loaded hyaluronan solid nanoemulsions (PTX-HSNs) were successfully fabricated for the delivery of PTX to improve ovarian cancer treatment via active tumor targeting. PTX-HSNs were fabricated using high-pressure homogenization with a microfluidizer and were lyophilized with d-mannitol. Hyaluronan was coated on
Joo-Eun Kim et al.
Biomolecules & therapeutics, 25(4), 411-416 (2017-02-17)
Paclitaxel (PTX) is a effectively chemotherapeutic agent which is extensively able to treat the non-small cell lung, pancreatic, breast and other cancers. But it is a practically insoluble drug with water solubility less than 1 µg/mL, which restricts its therapeutic
Jae Young Jeong et al.
Acta biomaterialia, 53, 414-426 (2017-02-22)
(3-Aminomethylphenyl)boronic acid (AMPB)-installed hyaluronic acid-ceramide (HACE)-based nanoparticles (NPs), including manassantin B (MB), were fabricated for tumor-targeted delivery. The amine group of AMPB was conjugated to the carboxylic acid group of hyaluronic acid (HA) via amide bond formation, and synthesis was
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