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702730

Sigma-Aldrich

tert-Butylchlorodiphenylsilane solution

1 M in methylene chloride

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100 ML
NOK 1,930.00

NOK 1,930.00


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100 ML
NOK 1,930.00

About This Item

Empirical Formula (Hill Notation):
C16H19ClSi
CAS Number:
Molecular Weight:
274.86
MDL number:
UNSPSC Code:
12352002
PubChem Substance ID:
NACRES:
NA.22

NOK 1,930.00


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form

liquid

Quality Level

concentration

1 M in methylene chloride

bp

40 °C

density

1.249 g/mL at 25 °C

SMILES string

CC(C)(C)[Si](Cl)(c1ccccc1)c2ccccc2

InChI

1S/C16H19ClSi/c1-16(2,3)18(17,14-10-6-4-7-11-14)15-12-8-5-9-13-15/h4-13H,1-3H3

InChI key

MHYGQXWCZAYSLJ-UHFFFAOYSA-N

Application

tert-Butylchlorodiphenylsilane can be used to prepare 1-benzyloxy-3-(tert-butyldiphenylsilyloxy)propan-2-ol, a key intermediate for the synthesis of mono-O-protected pyrimidine acyclic nucleosides.[1]

Signal Word

Danger

Hazard Statements

Hazard Classifications

Carc. 2 - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3

Target Organs

Central nervous system, Respiratory system

Storage Class Code

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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A new synthetic route towards the mono-O-protected anti-conformationally constrained pyrimidine acyclic nucleoside
Liu C, et al.
Chemical & Pharmaceutical Bulletin, 50(8), 1028-1030 (2002)

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