All Photos(1)
About This Item
Linear Formula:
CH3C6H4SO2Cl
CAS Number:
Molecular Weight:
190.65
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Assay
97%
refractive index
n20/D >1.5580 (lit.)
bp
254 °C (lit.)
density
1.320 g/mL at 25 °C (lit.)
SMILES string
Cc1ccccc1S(Cl)(=O)=O
InChI
1S/C7H7ClO2S/c1-6-4-2-3-5-7(6)11(8,9)10/h2-5H,1H3
InChI key
HDECRAPHCDXMIJ-UHFFFAOYSA-N
General description
o-Toluenesulfonyl chloride can be synthesized by reacting o-thiocresol in glacial acetic acid with chlorine. It participates in the preparation of 5-chloro-3-phenyl-2,1-benzisoxazole.
Application
o-Toluenesulfonyl chloride may be used in the synthesis of:
- oxazoline
- mesityl o-tolyl sulfone
- allyl o-toluenesulfonate
- 2-methyl-4′-t-butyldiphenyl sulfone
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Skin Corr. 1B
Storage Class Code
8A - Combustible corrosive hazardous materials
WGK
WGK 3
Flash Point(F)
230.0 °F - closed cup
Flash Point(C)
110 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
Cyclization of Acylaminoalkanols to 2-Oxazolines1.
Boyd RN and Rittner RC.
Journal of the American Chemical Society, 82(8), 2032-2034 (1960)
Intramolecular nucleophilic participation. V. The role of the ortho-substituent in the solvolysis of o-nitrobenzhydrl bromide and o-nitrobenzyl tosylate.
Mease AD, et al.
Journal of the American Chemical Society, 90(7), 1797-1801 (1968)
Asymmetric induction reactions. IV. Palladium-catalyzed asymmetric allylations of chiral enamines bearing phosphine groups.
Hiroi K and Abe J.
Chemical & Pharmaceutical Bulletin, 39(3), 616-621 (1991)
Gabriel Martínez-Edo et al.
Pharmaceutics, 12(11) (2020-11-06)
A pH-triggered mesoporous silica nanoparticle (MSN)-based nano-vehicle for the dual delivery of doxorubicin (DOX)/camptothecin-PEG (CPT-PEG) has been prepared. To enhance its selectivity, the nanoparticles were decorated with glycyrrhetinic acid (GA) to target HepG2 cells. The highly insoluble CPT was derivatized
The Metalation of 4-t-Butyldiphenyl Sulfone with n-Butyllithium1.
Shirley DA and Lehto EA.
Journal of the American Chemical Society, 79(13), 3481-3485 (1957)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service