All Photos(1)
About This Item
Linear Formula:
CH3CH2OCO(CH2)4CH(Cl)(CH2)2Cl
CAS Number:
Molecular Weight:
241.15
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
Recommended Products
Assay
95%
refractive index
n20/D 1.462 (lit.)
density
1.107 g/mL at 25 °C (lit.)
SMILES string
CCOC(=O)CCCCC(Cl)CCCl
InChI
1S/C10H18Cl2O2/c1-2-14-10(13)6-4-3-5-9(12)7-8-11/h9H,2-8H2,1H3
InChI key
RFYDWSNYTVVKBR-UHFFFAOYSA-N
Application
Ethyl 6,8-dichlorooctanoate may be used as a starting material in the synthesis of 6-selenolipoic acid[1] and α-lipoic acid derivatives, which show potent anticancer activity.[2]
It may also be used as a starting material to synthesize:
It may also be used as a starting material to synthesize:
- 6,8-Dibenzylmercaptooctanoic acid, an intermediate for the preparation of DL-α-lipoic acid.[3]
- Ethyl 5,7-dichloroheptanoate, an intermediate for the preparation of DL-1,2-dithiolane-3-butyric acid.[4]
- 7-Bromo-1,3-dichloroheptane, an intermediate for the preparation of DL-12-dithiolane-3-butanesulfonamide.[5]
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Chronic 2 - Skin Sens. 1
Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point(F)
230.0 °F - closed cup
Flash Point(C)
110 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Certificates of Analysis (COA)
Lot/Batch Number
Don't see the Right Version?
If you require a particular version, you can look up a specific certificate by the Lot or Batch number.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Synthesis of some monoselenolipoic acid derivatives and their biological evaluation as anticancer agents.
Xu F, et al.
J. Chem. Res. (M), 37(5), 311-314 (2013)
Synthesis of DL-1, 2-Dithiolane-3-caproic Acid and DL-1, 2-Dithiolane-3-butyric Acid, Homologs of a-Lipoic Acid.
Thomas RC and Reed LJ.
Journal of the American Chemical Society, 78(23), 6151-6153 (1956)
Syntheses of DL-a-lipoic acid.
Reed LJ and Niu CI.
Journal of the American Chemical Society, 77(2), 416-419 (1955)
Synthesis of DL-1, 2-Dithiolane-3-butanesulfonamide, an Analog of a-Lipoic Acid.
Thomas RC and Reed LJ.
Journal of the American Chemical Society, 78(23), 6150-6151 (1956)
Shi-Jie Zhang et al.
Bioorganic & medicinal chemistry letters, 20(10), 3078-3083 (2010-04-21)
alpha-Lipoic acid derivatives were synthesized and evaluated for their in vitro anticancer activities against NCI-460, HO-8910, KB, BEL-7402, and PC-3 cell lines. The results, for most compounds exhibited dose-dependent inhibitory property and several compounds had good inhibitions at the dose
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service
