All Photos(1)
About This Item
Linear Formula:
CH3OC10H6CO2H
CAS Number:
Molecular Weight:
202.21
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Assay
98%
mp
133-136 °C (lit.)
SMILES string
COc1cc2ccccc2cc1C(O)=O
InChI
1S/C12H10O3/c1-15-11-7-9-5-3-2-4-8(9)6-10(11)12(13)14/h2-7H,1H3,(H,13,14)
InChI key
RTBQQRFTCVDODF-UHFFFAOYSA-N
General description
3-Methoxy-2-naphthoic acid is a naphthoic acid derivative. 3-Methoxy-2-naphthoic acid can be prepared from 3-hydroxy-2-naphthoic acid, via methylation. It undergoes reduction under the following reaction conditions:
- in the presence of Li and NH4Cl to afford 1,2,3,4-tetrahydro-2-naphthoic acid
- by using Li, NH4Cl and anhydrous FeCl3 to afford 3-methoxy-1, 2-dihydro-2-naphthoic acid
- in anhydrous ether, liquid ammonia, lithium wire and anhydrous ethanol to afford 1,2,3,4-tetrahydro-2-naphthoic acid
Application
3-Methoxy-2-naphthoic acid may be used in the synthesis of N-[p-N,N-dimethylanilino)-3-methoxy-2-naphtho]hydroxamic acid (DAMNHA).
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Studies in metal-ammonia reduction-5: Reduction and reductive methylation of some naphthoic acids.
Murthy AR, et al.
Tetrahedron, 38(18), 2831-2836 (1982)
Extraction and spectrophotometric determination of vanadium (V) with N-[p-(N, N-dimethylanilino)-3-methoxy-2-naphtho] hydroxamic acid.
Abbasi S.
Analytical Chemistry, 48(4), 714-717 (1976)
J W Ellingboe et al.
Journal of medicinal chemistry, 36(17), 2485-2493 (1993-08-20)
A series of naphthalenyl 3H-1,2,3,5-oxathiadiazole 2-oxides was prepared and tested for antihyperglycemic activity in the db/db mouse, a model for type 2 (non-insulin dependent) diabetes mellitus. Substitution at the 1-, 5-, or 8-positions of the naphthalene ring with a halogen
Birch Reduction of 2-Naphthoic and of ortho-Methoxynaphthoic Acids.
Eliel EL and Hoover TE.
The Journal of Organic Chemistry, 24(7), 938-942 (1959)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service