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Sigma-Aldrich

2-Bromo-5-nitropyridine

99%

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About This Item

Empirical Formula (Hill Notation):
C5H3BrN2O2
CAS Number:
4487-59-6
Molecular Weight:
202.99
EC Number:
224-777-2
MDL number:
MFCD00006222
UNSPSC Code:
12352100
PubChem Substance ID:
24859471
NACRES:
NA.22

Assay

99%

form

solid

bp

145-147 °C/10 mmHg (lit.)

mp

139-141 °C (lit.)

SMILES string

[O-][N+](=O)c1ccc(Br)nc1

InChI

1S/C5H3BrN2O2/c6-5-2-1-4(3-7-5)8(9)10/h1-3H

InChI key

HUUFTVUBFFESEN-UHFFFAOYSA-N

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Application

2-Bromo-5-nitropyridine was used in preparation of boc-protected (piperazin-1-ylmethyl)biaryls via microwave-mediated Suzuki-Miyaura coupling with (boc-piperazin-1-ylmethyl)phenylboronic acid pinacol esters. It was also used in the synthesis of 2-pyridyl analogs.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301,H315,H319,H335

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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