276170

N,N-Dimethylbenzamide

99%

• Synonym(s): DMBZ
• Linear Formula: C₆H₅CON(CH₃)₂
• CAS Number: 611-74-5
• Molecular Weight: 149.19
• EC Number: 210-279-2
• MDL number: MFCD00008320
• UNSPSC Code: 12352100
• PubChem Substance ID: 24856689
• NACRES: NA.22

Properties

• Assay: 99%
• form: solid
• bp: 132-133 °C/15 mmHg (lit.)
• mp: 43-45 °C (lit.)
• SMILES string: CN(C)C(=O)c1ccccc1
• InChI: 1S/C9H11NO/c1-10(2)9(11)8-6-4-3-5-7-8/h3-7H,1-2H3
• InChI key: IMNDHOCGZLYMRO-UHFFFAOYSA-N

Description

General description

N,N-Dimethylbenzamide is a hydrotropic agent and its ability to solubilize drugs with low aqueous solubility has been investigated. It reacts with PhLnI complexes (Ln-Eu, Sm, Yb) to yield benzophenone in good yields. Deuterium exchange labelling experimets on N,N-dimethylbenzamide using [IrH₂(Me₂CO)₂(PPh₃)₂]BF₄ as catalyst and deuterium gas as the source of isotope has been conducted.

Application

Reagent for deoxygenation of secondary alcohols.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302,H315,H319,H335
• Precautionary Statements: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): 235.4 °F - closed cup
• Flash Point(C): 113 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves