This is not an application that is tested internally, but there is evidence in literature (Iwunze MO. The fluorescence study of the quenching of nanoemulsion by protoporphyrin IX (PPIX). Material Sci & Eng. 2022;6(3):97‒99. DOI: 10.15406/mseij.2022.06.00185) that concentrations between 6.45 x 10-7 M to 3.24 x 10-6 M PPIX are effective for quenching. Another author describes the quenching of protein fluorescence by PPIX by using a solution concentration range of 1×10−5 M to 3×10−4 M excited at 280 nm and 1x10−5 M to 3×10−4 M excited at 295 nm (Characteristics of the Protoporphyrin IX Binding Sites on Human Serum Albumin Using Molecular Docking, Molecules 2016, 21(11), 1519).
258385
Protoporphyrin IX disodium salt
≥90% (HPLC)
Synonym(s):
3,7,12,17-Tetramethyl-8,13-divinyl-2,18-porphinedipropionic acid disodium salt, Depocolin-S, Ooporphyrin disodium salt
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250 MG
NOK 527.00
1 G
NOK 1,800.00
5 G
NOK 5,930.00
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250 MG
NOK 527.00
1 G
NOK 1,800.00
5 G
NOK 5,930.00
About This Item
Empirical Formula (Hill Notation):
C34H32N4Na2O4
CAS Number:
Molecular Weight:
606.62
Beilstein:
5227034
EC Number:
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:
NACRES:
NA.23
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Quality Level
Assay
≥90% (HPLC)
form
powder
λmax
406 nm
storage temp.
2-8°C
SMILES string
[Na+].[Na+].Cc1c(CCC([O-])=O)c2cc3[nH]c(cc4nc(cc5[nH]c(cc1n2)c(C=C)c5C)c(C=C)c4C)c(C)c3CCC([O-])=O
InChI
1S/C34H34N4O4.2Na/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;;/h7-8,13-16,36-37H,1-2,9-12H2,3-6H3,(H,39,40)(H,41,42);;/q;2*+1/p-2/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-;;
InChI key
JZRNDUPVNXWZDY-HXFTUNQESA-L
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Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Hirotsugu Kobuchi et al.
PloS one, 7(11), e50082-e50082 (2012-11-29)
Accumulation of protoporphyrin IX (PpIX) in malignant cells is the basis of 5-aminolevulinic acid (ALA)-mediated photodynamic therapy. We studied the expression of proteins that possibly affect ALA-mediated PpIX accumulation, namely oligopeptide transporter-1 and -2, ferrochelatase and ATP-binding cassette transporter G2
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Protoporphyrin IX (PpIX) has been used as a sensitizer in photodynamic therapy (PDT) as well as in sonodynamic therapy (SDT). The photo-bleaching of PpIX has been well investigated in many experimental systems and some photo-products have also been identified in
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To study interaction of porphyrin with a protein, how should a solution of this compound be made for flourescence quenching?
1 answer-
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What is the water solubility of PPIX-disodium?
1 answer-
This chemical is known to be soluble in chloroform or methanol and slightly soluble in water. The concentration at which this product is solubilized is not determined.
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