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Key Documents

218693

Sigma-Aldrich

1-Aminocyclohexanecarboxylic acid

98%

Synonym(s):

Homocycloleucine

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About This Item

Linear Formula:
H2NC6H10CO2H
CAS Number:
Molecular Weight:
143.18
Beilstein:
2355692
EC Number:
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.22

Assay

98%

form

solid

reaction suitability

reaction type: solution phase peptide synthesis

mp

>300 °C (lit.)

application(s)

peptide synthesis

SMILES string

NC1(CCCCC1)C(O)=O

InChI

1S/C7H13NO2/c8-7(6(9)10)4-2-1-3-5-7/h1-5,8H2,(H,9,10)

InChI key

WOXWUZCRWJWTRT-UHFFFAOYSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Edyta Podstawka et al.
Biopolymers, 83(2), 193-203 (2006-06-03)
In this work, Raman spectroscopy (RS) was employed to characterize molecular structures of [Arg8]vasopressin (AVP) and its [Acc2,D-Arg8]AVP, [Acc3]AVP, and [Cpa1, Acc3]AVP analogues. The RS band assignments have been proposed. To determine the mechanism of adsorption of the above-mentioned compounds
M Sukumar et al.
Biochemical and biophysical research communications, 128(1), 339-344 (1985-04-16)
Analogs of chemotactic peptides (Formyl-Met-X-Phe-OMe) containing the stereochemically constrained residues alpha-aminoisobutyric acid (Aib), 1-aminocyclopentanecarboxylic acid (Acc5) and 1-aminocyclohexanecarboxylic acid (Acc6) at position 2 are compared with the parent sequence (X = Leu) for their ability to induce lysozyme release in
B Jastrzebska et al.
The journal of peptide research : official journal of the American Peptide Society, 62(2), 70-77 (2003-06-26)
In this study we describe the synthesis and some pharmacological properties of seven new analogues of arginine vasopressin (AVP) substituted in position 2 or 3 with 1-aminocyclohexane-1-carboxylic acid (Acc). All peptides were tested for the pressor, antidiuretic and uterotonic in
Olga Labudda et al.
Journal of peptide science : an official publication of the European Peptide Society, 12(12), 775-779 (2006-11-30)
A sterically constrained non-coded amino acid, 1-aminocyclopentane-1-carboxylic acid (Apc), was introduced in position 7 or 8 of the bradykinin (BK) B(2) receptor antagonist, [D-Arg(0), Hyp(3), Thi(5, 8), D-Phe(7)]BK, previously synthesized by Stewart's group. This modification is believed to reduce the
Nicolas Fabresse et al.
Journal of pharmaceutical and biomedical analysis, 141, 149-156 (2017-04-27)
Tranexamic acid is a widely used antifibrinolytic drug but its pharmacology and pharmacokinetics remains poorly understood. Owing to the recent knowledge on phospholipid-induced matrix effects during human plasma analysis, our aim was to develop a liquid chromatography-mass spectrometry method for

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