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About This Item
Linear Formula:
H2NNHC(=NH)NHNH2·HCl
CAS Number:
Molecular Weight:
125.56
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Assay
98%
mp
180-182 °C (dec.) (lit.)
solubility
water: soluble 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow
SMILES string
Cl.NNC(=N)NN
InChI
1S/CH7N5.ClH/c2-1(5-3)6-4;/h3-4H2,(H3,2,5,6);1H
InChI key
HAZRIBSLCUYMQP-UHFFFAOYSA-N
General description
1,3-Diaminoguanidine monohydrochloride undergoes condensation reaction with:
- 4-isothiocyanato-4-methylpentane-2-one to yield condensed pyrimidines
- various aldehydes and ketones to yield bis guanidine derivatives
Other Notes
Contains sodium chloride
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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K Kumari et al.
Diabetes, 40(8), 1079-1084 (1991-08-01)
Mono- and diaminoguanidine inhibited ambient glucose-induced glycosylated end product formation of albumin and collagen 125I-labeled albumin covalent binding in vitro. Diaminoguanidine was a stronger inhibitor than monoaminoguanidine. These compounds also inhibited rat eye lens aldose reductase activity in vitro noncompetitively
J Brimnes et al.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 107(6), 555-565 (1999-06-24)
Several N-N-and N-O-containing compounds were analysed for their ability to act as substrates for horseradish peroxidase and peroxidases in Mycobacterium tuberculosis extracts. Aminoguanidine, diaminoguanidine, isoniazid, hydroxylamine and hydrazine were found to be weak substrates for horseradish peroxidase in reaction I
María Paula Campestre et al.
Journal of plant physiology, 168(11), 1234-1240 (2011-02-18)
The possible relationship between polyamine catabolism mediated by copper-containing amine oxidase and the elongation of soybean hypocotyls from plants exposed to NaCl has been studied. Salt treatment reduced values of all hypocotyl growth parameters. In vitro, copper-containing amine oxidase activity
Synthesis of condensed pyrimidines and their evaluation for anti-inflammatory and analgesic activities.
Sondhi SM, et al.
Indian J. Chem. B, 47(1), 136-136 (2008)
Anthony J Lee et al.
Chemical research in toxicology, 18(12), 1927-1933 (2005-12-20)
It is established that aminoguanidine (AG), diaminoguanidine (DAG), and NG-amino-l-arginine (NAA) are metabolism-based inactivators of the three major isoforms of nitric oxide synthase (NOS). In the case of neuronal NOS (nNOS), heme alteration is known to be a major cause
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