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RAB1136

Sigma-Aldrich

Rat Adiponectin ELISA Kit

for cell culture supernatants, plasma, and serum samples

Synonym(s):

Adiponectin Assay, Rat ELISA

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

species reactivity

rat

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type cell culture supernatant(s)
sample type plasma
sample type serum sample(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.8 ng/ml

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

rat ... Adipoq(246253)

General description

This ELISA antibody pair detects Rat Adiponectin (ADIPOQ/ACRP30)

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

Biochem/physiol Actions

Adiponectin, also known as AdipoQ, is a plasma protein produced by adipocytes. Downregulation of adiponectin by mutation causes insulin resistance and type 2 diabetes. The expression level of adiponectin in plasma is lower in obesity. Adiponectin interacts with other proteins produced by adipocytes and is involved in triglyceride synthesis. Adiponectin in plasma lowers the expression of adhesion molecules in vascular endothelial cells and reduces the risk of atherogenic vascular diseases.

Other Notes

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

Pictograms

Corrosion
GHS05

Signal Word

Warning

Hazard Statements

H290

Precautionary Statements

P234 - P390

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Association of adiponectin mutation with type 2 diabetes: a candidate gene for the insulin resistance syndrome
Kondo H, et al.
Diabetes, 51(7), 2325-2328 (2002)
Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity
Arita Y, et al.
Biochemical and Biophysical Research Communications, 257(1), 79-83 (1999)
Genomic structure and mutations in adipose-specific gene, adiponectin
Takahashi M, et al.
International journal of obesity (2005), 24(7), 861-868 (2000)
Jóctan Pimentel Cordeiro et al.
PloS one, 17(8), e0271592-e0271592 (2022-08-12)
There are evidence that obese-resistant animals are more physically active, due to a higher rate of lipid oxidation. Efficiency in such pathways can favor greater spontaneous physical activity and, consequently, less body fat deposition. The aim of study was characterizing

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