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L0294

Sigma-Aldrich

Luxol® fast blue solution

liquid

Synonym(s):

Solvent blue 38

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About This Item

UNSPSC Code:
12171500
NACRES:
NA.47

product name

Luxol® fast blue solution, 1%

form

liquid

Quality Level

concentration

1%

density

0.800 g/cm3

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

General description

Luxol® fast blue solution is a copper phthalocyanine preferred for staining myelin in paraffin processed tissue. Its use is restricted to the tissues of the central nervous system.

Application

Ready-to-use stain for myelin and phospholipids. Luxol® fast blue solution has been used to stain brain tissue in order to analyse the degree of demyelination. It has also been used in histological analysis of adult zebrafish cord, to study time course after injury.

Legal Information

Luxol is a registered trademark of Rohm and Haas Co.

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 2

Target Organs

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

57.2 °F - closed cup

Flash Point(C)

14.0 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Bancroft's Theory and Practice of Histological Techniques E-Book (2018)
The relationship between the occurrence of intractable epilepsy with glial cells and myelin sheath--an experimental study
Hu X,et al.
European Review for Medical and Pharmacological Sciences, 20(21), 4516-4524 (2016)
Various Modes of Spinal Cord Injury to Study Regeneration in Adult Zebrafish
Hui, et al.
PLoS ONE, 20(21), 4516-4524 (2015)
X Hu et al.
European review for medical and pharmacological sciences, 20(21), 4516-4524 (2016-11-23)
The occurrence of epilepsy is associated with myelin sheath injury; oligodendrocyte (OL) is the main cell of myelin sheath; In this study, we observed the changes of OL, demyelination, and myelin associated protein in different stages of intractable epilepsy (IE)
Zhao-Lan Hu et al.
Theranostics, 11(2), 715-730 (2021-01-05)
Rationale: Brain-derived neurotrophic factor precursor (proBDNF) is expressed in the central nervous system (CNS) and the immune system. However, the role of proBDNF in the pathogenesis of multiple sclerosis (MS) is unknown. Methods: Peripheral blood and post-mortem brain and spinal

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