I2516
Isocitric Dehydrogenase (NADP) from porcine heart
lyophilized powder, 20-60 units/mg protein (biuret)
Synonym(s):
threo-Ds-Isocitrate: NADP+ oxidoreductase, ICDH, IDH
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About This Item
Recommended Products
form
lyophilized powder
specific activity
20-60 units/mg protein (biuret)
composition
Protein, ~20%
storage temp.
−20°C
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Quality
Highly purified
Essentially free of aconitase activity.
Essentially free of aconitase activity.
Unit Definition
One unit will convert 1.0 μmole of isocitrate to α-ketoglutarate per min at pH 7.4 at 37°C.
Physical form
Lyophilized powder containing sodium citrate and manganous sulfate
comparable product
inhibitor
Product No.
Description
Pricing
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Resp. Sens. 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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O Zalatimo et al.
Advances in experimental medicine and biology, 779, 267-289 (2013-01-05)
Primary brain tumors constitute a substantial public health problem with 66,290 cases diagnosed in the US in 2012, and 13,700 deaths recorded. With discovery of genetic factors associated with specific brain tumor subtypes, the goal of therapy is changing from
Lynn J Poole Perry et al.
American journal of ophthalmology, 155(3), 593-608 (2012-12-12)
To evaluate the cellular nature of and diagnostic terminology used in connection with acquired retinal "vasoproliferative tumors." Retrospective clinicopathologic study. Clinical records and microscopic slides of 4 enucleated globes were reviewed. Special stains and immunohistochemical probes for CD31, CD34, p53
Juan C Begara-Morales et al.
Journal of experimental botany, 64(4), 1121-1134 (2013-01-31)
Protein tyrosine nitration is a post-translational modification mediated by reactive nitrogen species (RNS) that is associated with nitro-oxidative damage. No information about this process is available in relation to higher plants during development and senescence. Using pea plants at different
Frank G Schaap et al.
Advances in anatomic pathology, 20(1), 32-38 (2012-12-13)
Heterozygous hotspot mutations in isocitrate dehydrogenases (IDH) IDH1 or IDH2 are frequently observed in specific types of cartilaginous tumors, gliomas, and leukemias. Mutant IDH enzyme loses its normal activity to convert isocitrate into α-ketoglutarate (αKG) and instead acquires the ability
Varuna Sipayya et al.
Journal of cancer research and therapeutics, 8(4), 598-601 (2013-01-31)
Mutations in the gene encoding isocitrate dehydrogenase (IDH1) have been reported in gliomas. This study analyses a series of 184 glioma cases in a tissue microarray (TMA)-based approach to assess the frequency of R132H point mutations in formalin-fixed, paraffin-embedded tissue
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