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G1876

Sigma-Aldrich

L-Glutamic acid γ-ethyl ester

Synonym(s):

L-Glutamic acid 5-ethyl ester

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About This Item

Linear Formula:
C2H5OCOCH2CH2CH(NH2)COOH
CAS Number:
1119-33-1
Molecular Weight:
175.18
Beilstein:
1725589
EC Number:
214-274-6
MDL number:
MFCD00037217
UNSPSC Code:
12352200
PubChem Substance ID:
24895078

application(s)

peptide synthesis

storage temp.

−20°C

SMILES string

CCOC(=O)CC[C@H](N)C(O)=O

InChI

1S/C7H13NO4/c1-2-12-6(9)4-3-5(8)7(10)11/h5H,2-4,8H2,1H3,(H,10,11)/t5-/m0/s1

InChI key

XMQUEQJCYRFIQS-YFKPBYRVSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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D Manahan-Vaughan
Neuropharmacology, 37(12), 1459-1464 (1999-01-14)
Activation of group 1 metabotropic glutamate receptors (mGluRs) has been shown to facilitate the induction of tetanically evoked long-term potentiation in vivo, whereas group 2 mGluR antagonists inhibit long-term depression (LTD) in the CA1 region. LTD has not been successfully
Cristina Marchetti et al.
Experimental brain research, 164(3), 406-410 (2005-07-02)
This study examined whether activation of group I metabotropic glutamate receptors (mGluRs) could modulate synaptic inhibition of spinal motoneurons in the neonatal rat isolated spinal cord. Recurrent inhibitory postsynaptic potentials (IPSPs) generated by Renshaw cells were evoked via antidromic stimulation
Rebecca J Chapman et al.
The European journal of neuroscience, 26(8), 2257-2268 (2007-09-27)
We have explored the potential involvement of the three main classes of metabotropic glutamate receptor in the modulation of a spinal locomotor network using tadpoles of the anuran amphibian Xenopus laevis. Selective activation of group I receptors in Xenopus embryos
Vilen A Movsesyan et al.
Journal of neurotrauma, 23(2), 117-127 (2006-03-01)
The effects of group II mGluR activation by selective agonist (-)-2-oxa-4-aminobicyclo[3.1. 0]hexane-4,6-dicarboxylate (LY379268) were examined in a mouse model of controlled cortical impact (CCI)-induced brain injury and in primary neuronal/glial and neuronal cultures subjected to mechanical trauma. Systemic administration of
H Thompson et al.
Neuropharmacology, 47(6), 822-832 (2004-11-06)
Previous work from this laboratory indicates that Group II/III metabotropic glutamate (mGlu) receptors modulate responses of SC neurones to visual stimuli in vivo. It is thought that tonic levels of glutamate may be sufficient to activate some mGlu receptors. We
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