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EMU061791

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Ptpn1

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CGGAACAGGTACCGAGATGTCAGCCCTTTTGACCACAGTCGGATTAAATTGCACCAGGAAGATAATGACTATATCAATGCCAGCTTGATAAAAATGGAAGAAGCCCAGAGGAGCTATATTCTCACCCAGGGCCCTTTACCAAACACATGTGGGCACTTCTGGGAGATGGTGTGGGAGCAGAAGAGCAGGGGCGTGGTCATGCTCAACCGCATCATGGAGAAAGGCTCGTTAAAATGTGCCCAGTATTGGCCACAGCAAGAAGAAAAGGAGATGGTCTTTGATGACACAGGTTTGAAGTTGACACTAATCTCTGAAGATGTCAAGTCATATTACACAGTACGACAGTTGGAGTTGGAAAACCTGACTACCAAGGAGACTCGAGAGATCCTGCCTTTCCACTACACC

Ensembl | mouse accession no.

ENSMUSG00000027540

NCBI accession no.

NM_011201

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... PTPN1(19246) , Ptpn1(19246)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Liza D Morales et al.
PloS one, 9(5), e97104-e97104 (2014-05-09)
To maintain tissue homeostasis, apoptosis is functionally linked to the cell cycle through the retinoblastoma (Rb)/E2F pathway. When the Rb tumor suppressor protein is functionally inactivated, E2F1 elicits an apoptotic response through both intrinsic (caspase-9 mediated) and extrinsic (caspase-8 mediated)
Xiaoyan Zhang et al.
Scientific reports, 5, 12987-12987 (2015-08-12)
Renal mesangial cells (RMCs) constitute a population of cells in glomerular mesangium. Inflammatory cytokines produced by RMCs play a vital role in renal inflammation. miRNAs are key regulators of inflammatory cytokine expression. The abnormal expression of renal miRNAs and the

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