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EHU026931

Sigma-Aldrich

MISSION® esiRNA

targeting human SMC6

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

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product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

TGAGGCAGTACCAAGAAGCAAGAGAGACCTATCTTGATCTGGATAGTAAAGTGAGGACTTTAAAAAAGTTTATTAAATTACTGGGAGAAATCATGGAGCACAGATTCAAGACATATCAACAATTTAGAAGGTGTTTGACTTTACGATGCAAATTATACTTTGACAACTTACTATCTCAGCGGGCCTATTGTGGAAAAATGAATTTTGACCACAAGAATGAAACTCTAAGTATATCAGTTCAGCCTGGAGAAGGAAATAAAGCTGCTTTCAATGACATGAGAGCCTTGTCTGGAGGTGAACGTTCTTTCTCCACAGTGTGTTTTATTCTTTCCCTGTGGTCCATCGCAGAATCTCCTTTCAGATGCCTGGATGAATTTGATGTCTACATGGATATGGTTAATAGGAGAATTGCCATGGACTTGATACTGAAGATGGCAGATTCCCAGCGTTTTAGACAGTTTATCTTGCTCACACCTCAAAGCATGA

Ensembl | human accession no.

NCBI accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Ryan T Gibson et al.
Pathogens (Basel, Switzerland), 9(10) (2020-10-01)
The multi-subunit structural maintenance of chromosomes (SMC) 5/6 complex includes SMC6 and non-SMC element (NSE)3. SMC5/6 is essential for homologous recombination DNA repair and functions as an antiviral factor during hepatitis B (HBV) and herpes simplex-1 (HSV-1) viral infections. Intriguingly

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