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C1011

Sigma-Aldrich

N-Cyclohexyl-N′-(2-morpholinoethyl)carbodiimide metho-p-toluenesulfonate

≥97% (CHN)

Synonym(s):

N-Cyclohexyl-N′-(β-[N-methylmorpholino]ethyl)carbodiimide p-toluenesulfonate, CMC, CME-CDI

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About This Item

Empirical Formula (Hill Notation):
C14H26N3O · C7H7O3S
CAS Number:
2491-17-0
Molecular Weight:
423.57
Beilstein:
3872192
EC Number:
219-650-3
MDL number:
MFCD00011979
UNSPSC Code:
12352200
PubChem Substance ID:
24892296

Assay

≥97% (CHN)

form

powder

technique(s)

ligand binding assay: suitable

color

white

mp

109-111 °C

application(s)

peptide synthesis

storage temp.

−20°C

SMILES string

Cc1ccc(cc1)S([O-])(=O)=O.C[N+]2(CCOCC2)CCN=C=NC3CCCCC3

InChI

1S/C14H26N3O.C7H8O3S/c1-17(9-11-18-12-10-17)8-7-15-13-16-14-5-3-2-4-6-14;1-6-2-4-7(5-3-6)11(8,9)10/h14H,2-12H2,1H3;2-5H,1H3,(H,8,9,10)/q+1;/p-1

InChI key

GBCAVSYHPPARHX-UHFFFAOYSA-M

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Application

Water-soluble condensing reagent for peptide synthesis, reagent used for coupling ligands to carriers in affinity chromatography.

Biochem/physiol Actions

N-Cyclohexyl-N′-(2-morpholinoethyl)carbodiimide (CMCT) selectively modifies/derivitizes all pseudouridine, thiouridine and 2-methylthio-6-isopentenyladenosine nucleosides for detection by methods such as matrix-assisted laser desorption/ionization mass spectrometry. CMCT, a water-soluble condensing reagent for peptide synthesis, is used as a reagent for coupling ligands to carriers in affinity chromatography.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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