C0791
Monoclonal Anti-Cytokeratin Peptide 13 antibody produced in mouse
clone KS-1A3, ascites fluid
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About This Item
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biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
KS-1A3, monoclonal
contains
15 mM sodium azide
species reactivity
human
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
indirect immunofluorescence: 1:100 using formalin-fixed, paraffin-embedded human tissue sections.1
microarray: suitable
isotype
IgG1
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... KRT13(3860)
Specificity
The antibody reacts with squamous, non-keratinized epithelium, transitional epithelium, pseudostratified epithelium, and myoepithelium.
Immunogen
cultured human epidermoid carcinoma cell line A-431.
Application
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)
Immunofluorescence (1 paper)
Monoclonal Anti-Cytokeratin Peptide 13 antibody produced in mouse is suitable for the following applications:
- Immunohistochemistry (formalin-fixed, paraffin-embedded sections)
- Indirect immunofluorescence at a working dilution of 1:100 using formalin-fixed, paraffin-embedded human tissue sections.
- Microarray
Biochem/physiol Actions
Cytokeratins are proteins of keratin-containing intermediate filaments that provide mechanical support and other additional functions in epithelial cells. It is found in the intracytoplasmic cytoskeleton of epithelial tissue. Epithelial tissue expresses cytokeratin subunits in a specific and stable pattern. Cytokeratins along with vimentin are involved in cell proliferation, migration and differentiation of preodontoblasts and preameloblasts. The intermediate-sized filaments are abundant in human endothelial cells and are mostly of vimentin type.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Huan He et al.
The Journal of biological chemistry, 290(21), 13567-13577 (2015-04-09)
Squamous cell differentiation requires the coordinated activation and repression of genes specific to the differentiation process; disruption of this program accompanies malignant transformation of epithelium. The exploration of genes that control epidermal proliferation and terminal differentiation is vital to better
Helen M Rigden et al.
PloS one, 11(5), e0156009-e0156009 (2016-05-27)
To quantify the extent of squamous metaplasia in bronchial biopsies and relate it to the presence of chronic obstructive pulmonary disease (COPD), a smoking-related pathology. Bronchial biopsies (n = 15 in each group) from smokers with COPD GOLD stage1 and
Aurélie Avril-Delplanque et al.
Stem cells (Dayton, Ohio), 23(7), 992-1001 (2005-07-27)
Airway epithelium stem cells have not yet been prospectively identified, but it is generally assumed that both secretory and basal cells have the capacity to divide and differentiate. Previously, we developed a test for progenitor cells of the human airway
S Spuler et al.
The American journal of pathology, 148(5), 1359-1365 (1996-05-01)
To study the possible role of thymomas and of extrathymomal thymic tissue in the development and maintenance of myasthenia gravis, we transplanted fragments of either tissue into SCID mice and monitored the production of anti-acetylcholine receptor antibodies in the recipients.
Debarchana Saha et al.
PloS one, 12(2), e0171084-e0171084 (2017-02-09)
Hemoglobin (Hb) is a major protein involved in transport of oxygen (O2). It consists of Hb-α and Hb-β subunits, which are normally expressed by cells of erythroid lineage. However, till recently, it was not known whether non-erythroid cells like vaginal
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