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A0796

Sigma-Aldrich

p-Aminomethylbenzenesulfonamide–Agarose

saline suspension

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About This Item

MDL number:
UNSPSC Code:
23151817

form

saline suspension

extent of labeling

≥6 mg per mL

matrix

crosslinked 4% beaded agarose

matrix activation

cyanogen bromide

matrix attachment

amino

matrix spacer

1 atom

storage temp.

2-8°C

Application

p-Aminomethylbenzenesulfonamide is an agarose in saline suspension that can be used in affinity chromatography, protein chromatography and specialty resins. p-Aminomethylbenzenesulfonamide has been used in studies assessing inhibition of mitochondrial carbonic anhydrase and ureagenesis.

Physical form

Suspension in 0.5 M NaCl containing preservative.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Skin Sens. 1

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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B E Alber et al.
Proceedings of the National Academy of Sciences of the United States of America, 91(15), 6909-6913 (1994-07-19)
Carbonic anhydrase (CA) from acetate-grown Methanosarcina thermophila was purified > 10,000-fold (22% recovery) to apparent homogeneity with a specific activity of 4872 units/mg. The estimated native molecular mass of the enzyme is 84 kDa based on gel filtration chromatography. SDS/PAGE
L G Puskás et al.
Microbiology (Reading, England), 146 ( Pt 11), 2957-2966 (2000-11-07)
Intact cells of the purple non-sulfur bacterium Rhodopseudomonas palustris growing anaerobically, but not aerobically, contain carbonic anhydrase (CA) activity. The native enzyme was purified >2000-fold to apparent homogeneity and found to be a dimer with an estimated molecular mass of
S J Dodgson
Journal of applied physiology (Bethesda, Md. : 1985), 63(5), 2134-2141 (1987-11-01)
The amount of urea synthesized in intact guinea pig hepatocytes in 60 min ([urea]t=60), was determined at 37 degrees C in Krebs-Henseleit buffer plus (in mM) 10 NH4Cl, 5 lactate, and 10 ornithine in 5% CO2-95% O2. The concentrations of
S J Dodgson et al.
Journal of applied physiology (Bethesda, Md. : 1985), 60(2), 646-652 (1986-02-01)
The amount of urea produced in 60 min, [urea]t = 60, from intact guinea pig hepatocytes incubated in NH4Cl, oleate, lactate, NaHCO3, and ornithine at 37 degrees C at pH 7.1 is decreased by ethoxzolamide (EZ): Ki,EZ [urea]t = 60
B Ulmasov et al.
Proceedings of the National Academy of Sciences of the United States of America, 97(26), 14212-14217 (2000-12-20)
Carbonic anhydrase XII (CA XII) is a transmembrane glycoprotein with an active extracellular CA domain that is overexpressed on cell surfaces of certain cancers. Its expression has been linked to tumor invasiveness. To characterize its catalytic properties, we purified recombinant

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