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Abamectin

PESTANAL®, analytical standard

Synonym(s):

Avermectin B1

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

storage temp.

−20°C

SMILES string

CCC(C)C1O[C@@]2(C[C@@H]3CC(C\C=C(C)\[C@@H](O[C@H]4C[C@H](OC)[C@@H](O[C@H]5C[C@H](OC)[C@@H](O)[C@H](C)O5)[C@H](C)O4)[C@@H](C)\C=C\C=C6/COC7[C@H](O)C(C)=CC(C(=O)O3)[C@]67O)O2)C=C[C@@H]1C

InChI

1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12+,27-15+,32-14+/t25-,26-,28-,30-,31-,33+,34-,35?,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1

InChI key

RRZXIRBKKLTSOM-RDKIRRGNSA-N

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General description

Abamectin (MK-0936) belongs to avermectin family. This family have a macrocycle as backbone with a spiroketal unit, a hexahydrobenzofuran unit and disaccharide substitute in general. MK-0936 is a natural fermenting product which can be produced by Streptomyces avermitilis.

Application

Abamectin has been used as standard in liquid chromatography–electrospray tandem mass spectrometry LC–ESI-MS–MS method for determination of abamectin residues in orange samples.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 1

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Determination of abamectin and azadirachtin residues in orange samples by liquid chromatography?electrospray tandem mass spectrometry.
Pozo, O. J., et al.
Journal of Chromatography A, 992.1, 133-140 (2003)
W Dermauw et al.
Insect biochemistry and molecular biology, 42(7), 455-465 (2012-04-03)
The cys-loop ligand-gated ion channel (cysLGIC) super family of Tetranychus urticae, the two-spotted spider mite, represents the largest arthropod cysLGIC super family described to date and the first characterised one within the group of chelicerates. Genome annotation, phylogenetic analysis and
Marcos A Maioli et al.
Toxicology in vitro : an international journal published in association with BIBRA, 27(2), 570-579 (2012-11-13)
Abamectin (ABA), which belongs to the family of avermectins, is used as a parasiticide; however, ABA poisoning can impair liver function. In a previous study using isolated rat liver mitochondria, we observed that ABA inhibited the activity of adenine nucleotide
Juliana C Castanha Zanoli et al.
Toxicology in vitro : an international journal published in association with BIBRA, 26(1), 51-56 (2011-10-26)
Abamectin (ABA) is a macrocyclic lactone of the avermectin family used worldwide as an antiparasitic agent in farm animals and pets and as the active ingredient of insecticides and nematicides. In this study, the effects of abamectin on the bioenergetics
S D George et al.
Veterinary parasitology, 188(1-2), 190-193 (2012-03-31)
Anthelmintic resistance by gastrointestinal nematodes of sheep continues to be an issue of global interest. While the recent introduction in some countries of one or two new anthelmintic classes (amino-acetonitrile derivatives [AAD] and spiroindoles [SI]) has been welcomed, it is

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