AB5852
Anti-SHANK1a Antibody, NT
Chemicon®, from rabbit
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About This Item
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biological source
rabbit
Quality Level
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
rat
manufacturer/tradename
Chemicon®
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
rat ... Shank1(78957)
General description
Shank is a novel family of postsynaptic density proteins (PSD) that bind to PDS-95-associated protein GKAP. Its putative function is to act as a scaffold protein in the PSD to cross-link NMDA receptors/PSD-95 complexes and couple them to regulators of the actin cytoskeleton. Shank1a is a splice variant of Shank1.
Specificity
Recognizes Shank1a, N-terminal.
Immunogen
Epitope: N-terminus
Synthetic peptide corresponding to the N-terminus of rat Shank1a.
Application
Anti-SHANK1a Antibody, N-terminus is an antibody against SHANK1a for use in WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Synapse & Synaptic Biology
Synapse & Synaptic Biology
Western blotting: 1:500-1:1,000
Optimal working dilutions must be determined by the end user.
Optimal working dilutions must be determined by the end user.
Physical form
Format: Purified
Purified immunoglobulin. Liquid in PBS containing 0.02% sodium azide.
Storage and Stability
Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Journal of immunology (Baltimore, Md. : 1950), 180(10), 6447-6451 (2008-05-06)
MHC class I molecules (MHC-I) have been implicated in nervous system development in the mouse. In this study we present evidence for the interaction of MHC-I with the NK cell receptor Ly49 in primary cortical neuronal cultures. We show that
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