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810187P

Avanti

TopFluor™ PI

Avanti Research™ - A Croda Brand 810187P, powder

Synonym(s):

1-oleoyl-2-{6-[4-(dipyrrometheneboron difluoride)butanoyl]amino}hexanoyl-sn-glycero-3-phosphoinositol (ammonium salt)

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About This Item

Empirical Formula (Hill Notation):
C50H84BF2N4O14P
CAS Number:
2260795-33-1
Molecular Weight:
1045.00
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 50 μg (with stopper and crimp cap (810187P-50ug))

manufacturer/tradename

Avanti Research™ - A Croda Brand 810187P

shipped in

dry ice

storage temp.

−20°C

General description

Phosphatidylinositol (PI) is commonly found in animal tissues and bacteria. PI is soluble in water and chloroform/methanol.

Application

TopFluor™ PI or 1-oleoyl-2-{6-[4-(dipyrrometheneboron difluoride)butanoyl]amino}hexanoyl-sn-glycero-3-phosphoinositol (ammonium salt) has been used as a fluorescent lipid in living cells to analyse the cellular localization of phosphatidylinositol (PI).

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (810187P-50ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Lipids of membranes: Chemistry, biological role and applications as drug carriers
Hatziantonioy S and Demetzos C
Studies in Natural Products Chemistry, 34, 173-202 (2009)
Probing the subcellular distribution of phosphatidylinositol reveals a surprising lack at the plasma membrane.
James PZ, et al.
The Journal of Cell Biology, 219(3), e201906127-e201906127 (2020)
James P Zewe et al.
The Journal of cell biology, 219(3) (2020-03-27)
The polyphosphoinositides (PPIn) are central regulatory lipids that direct membrane function in eukaryotic cells. Understanding how their synthesis is regulated is crucial to revealing these lipids' role in health and disease. PPIn are derived from the major structural lipid, phosphatidylinositol

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