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Sigma-Aldrich

Upconversion Nanoparticles

Silica coated NaYF4-Yb,Er@NaYF4, fluorescence λex 980 nm, green light

Synonym(s):

UCNPs

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About This Item

UNSPSC Code:
12352302
NACRES:
NA.23

Quality Level

100

concentration

2 mg/mL

size

50 nm ± 15%

matrix active group

OH surface treatment

solubility

water: dispersible

fluorescence

λex 980 nm (green)
λem 540 nm
λem 650 nm

storage temp.

2-8°C

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Application

Upconversion nanoparticles (ucnps), are the result of a unique optical process in which near-infrared (NIR) light excitation is converted into visible and/or UV emission. Upconversion (UC) utilizes sequential absorption of multiple photons utilizing both lifetime and real ladder-like energy levels of ions in a host lattice to produce a higher energy anti-Stokes luminescence. This optical features of UCNPs, results in deep tissue penetration and minimal autofluorescence background, for a broad range of applications of UCNP in diagnostics and biomedical imaging systems.

Applications include:
  • Fluorescent microscopy
  • Deep-tissue bioimaging
  • Nanomedicine
  • Optogenetic
  • Security labelling
  • Volumetric display

Legal Information

Product of RuixiBiotechCo. Ltd

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

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Shihui Wen et al.
Nature communications, 9(1), 2415-2415 (2018-06-22)
Lanthanide-doped upconversion nanoparticles (UCNPs) are capable of converting near-infra-red excitation into visible and ultraviolet emission. Their unique optical properties have advanced a broad range of applications, such as fluorescent microscopy, deep-tissue bioimaging, nanomedicine, optogenetics, security labelling and volumetric display. However
Christoph Drees et al.
Angewandte Chemie (International ed. in English), 55(38), 11668-11672 (2016-08-12)
Upconversion nanoparticles (UCNPs) convert near-infrared into visible light at much lower excitation densities than those used in classic two-photon absorption microscopy. Here, we engineered <50 nm UCNPs for application as efficient lanthanide resonance energy transfer (LRET) donors inside living cells. By
Upconversion nanoparticles: design, nanochemistry, and applications in theranostics.
Guanying Chen et al.
Chemical reviews, 114(10), 5161-5214 (2014-03-13)
Daniel J Gargas et al.
Nature nanotechnology, 9(4), 300-305 (2014-03-19)
Imaging at the single-molecule level reveals heterogeneities that are lost in ensemble imaging experiments, but an ongoing challenge is the development of luminescent probes with the photostability, brightness and continuous emission necessary for single-molecule microscopy. Lanthanide-doped upconverting nanoparticles overcome problems
Yujia Liu et al.
Nature, 543(7644), 229-233 (2017-02-23)
Lanthanide-doped glasses and crystals are attractive for laser applications because the metastable energy levels of the trivalent lanthanide ions facilitate the establishment of population inversion and amplified stimulated emission at relatively low pump power. At the nanometre scale, lanthanide-doped upconversion

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