366951
4-(Trifluoromethoxy)phenylhydrazine hydrochloride
98%
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About This Item
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Assay
98%
form
solid
mp
230 °C (lit.)
functional group
fluoro
hydrazine
SMILES string
Cl.NNc1ccc(OC(F)(F)F)cc1
InChI
1S/C7H7F3N2O.ClH/c8-7(9,10)13-6-3-1-5(12-11)2-4-6;/h1-4,12H,11H2;1H
InChI key
KQXZVSQCMVKMBK-UHFFFAOYSA-N
General description
4-(Trifluoromethoxy)phenylhydrazine hydrochloride is an organic building block.
Application
4-(Trifluoromethoxy)phenylhydrazine hydrochloride may be used in the synthesis of pyrazole-containing bisphosphonate (N-BPs) esters.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Organic & biomolecular chemistry, 10(38), 7730-7738 (2012-08-21)
An efficient general synthetic approach has been developed to synthesize pyrazole-containing bisphosphonate (N-BPs) esters from chromenone derivatives via a sequential two-step reaction in one pot at ambient temperature in good to excellent yields. This protocol provides a new convenient method
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