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P3794

Sigma-Aldrich

Procyclidine hydrochloride

Synonym(s):

α-Cyclohexyl-α-phenyl-1-pyrrolidinepropanol

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About This Item

Empirical Formula (Hill Notation):
C19H29NO · HCl
CAS Number:
1508-76-5
Molecular Weight:
323.90
EC Number:
216-141-8
MDL number:
MFCD00079236
UNSPSC Code:
12352200
PubChem Substance ID:
24898455
NACRES:
NA.77

form

solid

Quality Level

100

storage temp.

2-8°C

SMILES string

Cl.OC(CCN1CCCC1)(C2CCCCC2)c3ccccc3

InChI

1S/C19H29NO.ClH/c21-19(17-9-3-1-4-10-17,18-11-5-2-6-12-18)13-16-20-14-7-8-15-20;/h1,3-4,9-10,18,21H,2,5-8,11-16H2;1H

InChI key

ZFSPFXJSEHCTTR-UHFFFAOYSA-N

Gene Information

human ... CHRM1(1128)

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Biochem/physiol Actions

Procyclidine is a synthetic anti-cholinergic agent and atropine-like antispasmodic. It exhibits therapeutic effects against Parkinson′s disease and schizophrenia. Procyclidine acts as a muscarinic receptor antagonist. It also affects N-methyl-D-aspartate (NMDA) glutamine and nicotinic acetylcholine receptors to a lower extent.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Effects of procyclidine on eye movements in schizophrenia
Ettinger U, et al.
Neuropsychopharmacology, 28(12), 2199-2208 (2003)

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