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32802

Supelco

Triclabendazole

VETRANAL®, analytical standard

Synonym(s):

5-Chloro-6-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole

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About This Item

Empirical Formula (Hill Notation):
C14H9Cl3N2OS
CAS Number:
68786-66-3
Molecular Weight:
359.66
MDL number:
MFCD00864519
UNSPSC Code:
41116107
PubChem Substance ID:
329754333
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

SMILES string

CSc1nc2cc(Cl)c(Oc3cccc(Cl)c3Cl)cc2[nH]1

InChI

1S/C14H9Cl3N2OS/c1-21-14-18-9-5-8(16)12(6-10(9)19-14)20-11-4-2-3-7(15)13(11)17/h2-6H,1H3,(H,18,19)

InChI key

NQPDXQQQCQDHHW-UHFFFAOYSA-N

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General description

Chemical structure: benzimidazole

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCH3573
BCCC1583
BCBS2918V
SZBD352XV
SZBD246XV

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Keyvan Aminian et al.
Annals of hepatology, 11(3), 395-398 (2012-04-07)
Here we report a rare case of living Fasciola hepatica in biliary tract. The patient was in acute phase of infection and treated successfully with 10 mg/kg oral triclabendazole after the fluke was extracted using endoscopic retrograde cholangiopancreatography (ERCP).
Michelle Whelan et al.
Journal of chromatography. A, 1275, 41-47 (2013-01-08)
Triclabendazole is the only anthelmintic drug, which is active against immature, mature and adult stages of fluke. The objective of this work was to develop an analytical method to quantify and confirm the presence of triclabendazole residues around the MRL.
Apparent triclabendazole-resistant human Fasciola hepatica infection, the Netherlands.
Annemarie J S Winkelhagen et al.
Emerging infectious diseases, 18(6), 1028-1029 (2012-05-23)
R Daniel et al.
The Veterinary record, 171(6), 153-153 (2012-07-14)
A faecal egg count reduction test, using composite samples, was developed in order to assess the efficacy of the flukicide, triclabendazole (TCBZ) on commercial sheep farms in England and Wales. First, a comparison between individual counts and composite counts was
Fidel Villegas et al.
PLoS neglected tropical diseases, 6(8), e1720-e1720 (2012-08-11)
The Bolivian northern Altiplano is characterized by a high prevalence of Fasciola hepatica infection. In order to assess the feasibility, safety and efficacy of large-scale administration of triclabendazole as an appropriate public health measure to control morbidity associated with fascioliasis
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