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Key Documents

860620P

Avanti

Lyso SM (dihydro) (d18:0)

Avanti Research - A Croda Brand, powder

Synonym(s):

Sphinganine Phosphorylcholine

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About This Item

Empirical Formula (Hill Notation):
C23H51N2O5P
CAS Number:
Molecular Weight:
466.64
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

99% (TLC)

form

powder

packaging

1 ea of 5 mg (860620P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand

lipid type

deuterated lipids
sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](CCCCCCCCCCCCCCC)(O)[C@@]([H])(N)COP([O-])(OCC[N+](C)(C)C)=O

General description

Lyso-dihydro-Sphingomyelin (lyso-dihydro-SM) is an analog of Lyso sphingomyelin (Lyso-SM). Lyso-SM is a derivative of sphingomyelin.

Biochem/physiol Actions

Lyso sphingomyelin (Lyso-SM) is involved in cellular functioning of heart, brain, blood vessels and skin. It also acts as a lipid mediator.

Packaging

5 mL Clear Glass Sealed Ampule

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sphingosylphosphocholine reduces the calcium ion requirement for activating tissue transglutaminase
Lai T S, et al.
The Journal of biological chemistry, 272(26), 16295-16300 (1997)
A novel enzyme that cleaves the N-acyl linkage of ceramides in various glycosphingolipids as well as sphingomyelin to produce their lyso forms.
Ito M
The Journal of Biological Chemistry, 270(41), 24370-24374 (1995)
Lyso-sphingomyelin is elevated in dried blood spots of Niemann-Pick B patients
Chuang W L, et al.
Molecular Genetics and Metabolism, 111(2), 209-211 (2014)

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