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790427P

Avanti

06:0 PC-d22

Avanti Research - A Croda Brand 790427P, powder

Synonym(s):

1,2-dihexanoyl-d22-sn-glycero-3-phosphocholine

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About This Item

Empirical Formula (Hill Notation):
C20H18NO8PD22
CAS Number:
Molecular Weight:
475.64
UNSPSC Code:
12352211
NACRES:
NA.25

Pricing and availability is not currently available.

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (790427P-10mg)

manufacturer/tradename

Avanti Research - A Croda Brand 790427P

shipped in

dry ice

storage temp.

−20°C

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This Item
EP4925000162EP4925000022EP4924000010
feature

single-channel, fixed

feature

single-channel, fixed

feature

single-channel, fixed

feature

includes epT.I.P.S.® box, single-channel, variable

volume

(2.5 mL)

volume

(2 mL)

volume

(2 μL)

volume

(0.1-2.5 μL)

packaging

pack of 1 ea

packaging

pack of 1 ea

packaging

pack of 1 ea

packaging

pack of 1 ea

color

red

color

red

color

dark gray

color

dark gray

General description

1,2-dihexanoyl-sn-glycero-3-phosphocholine (06:0 PC) is a hydrophobic acyl chain containing phospholipid with a critical micelle concentration of 15 mM.[1] 06:0 PC-d22 is the deuterated form of 06:0 PC.
Deuterated fatty acids experience exchange of the deuteriums on the alpha carbon to the carbonyl, i.e., C2 position, and will therefore be a mixture of compounds that are fully deuterated and partially deuterated at that position.

Application

06:0 PC-d22 has been used in small isotropic bicelles preparation for C-peptide membrane interaction studies by diffusion nuclear magnetic resonance (NMR) and 2D total correlation spectroscopy (TOCSY)[2] and in in situ infrared (IR) absorption spectra.[3] It may be used as an internal standard in capillary electrophoresis time of flight mass spectrometer (CE-TOFMS) and liquid chromatography with tandem mass spectrometry (LC-MS-MS) for the analysis of algal lipidome.[4]

Biochem/physiol Actions

1,2-dihexanoyl-sn-glycero-3-phosphocholine (06:0 PC) bicelle with 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) takes a disc like conformation.[5] Phosphocholine (PC) is the catabolized product of phosphatidylcholine (lecithin). PC mediates immune response and acts as a ligand for nicotinic acetylcholine receptors (nAChR).[6]

Packaging

5 mL Clear Glass Sealed Ampule (790427P-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids


Certificates of Analysis (COA)

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Sofia Unnerståle et al.
Journal of biophysics (Hindawi Publishing Corporation : Online), 2012, 185907-185907 (2012-08-01)
C-peptide is the connecting peptide between the A and B chains of insulin in proinsulin. In this paper, we investigate the interaction between C-peptide and phospholipid bicelles, by circular dichroism and nuclear magnetic resonance spectroscopy, and in particular the pH
Takuro Ito et al.
Metabolomics : Official journal of the Metabolomic Society, 9(Suppl 1), 178-187 (2013-03-07)
Oil-rich algae have promising potential for a next-generation biofuel feedstock. Pseudochoricystis ellipsoidea MBIC 11204, a novel unicellular green algal strain, accumulates a large amount of oil (lipids) in nitrogen-deficient (-N) conditions. Although the oil bodies are easily visualized by lipophilic
Soichiro Matsunaga et al.
Langmuir : the ACS journal of surfaces and colloids, 33(46), 13157-13167 (2017-08-02)
In situ dynamic observation of model biological cell membranes, formed on a water/gold substrate interface, has been performed by the combination of electrochemical scanning tunneling microscopy and reflection infrared absorption vibrational spectroscopy. Monolayers of 1,2-dihexanoyl-sn-glycero-3-phosphocholine (DHPC) were formed on alkanethiol-modified
K Richter et al.
Scientific reports, 6, 28660-28660 (2016-06-29)
We demonstrated previously that phosphocholine and phosphocholine-modified macromolecules efficiently inhibit ATP-dependent release of interleukin-1β from human and murine monocytes by a mechanism involving nicotinic acetylcholine receptors (nAChR). Interleukin-1β is a potent pro-inflammatory cytokine of innate immunity that plays pivotal roles
Systematic Characterization of DMPC/DHPC Self-Assemblies and Their Phase Behaviors in Aqueous Solution
Taguchi S, et al.
Colloids and Interfaces, 2(4), 73-73 (2018)

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