658235

Lithium dimethylaminoborohydride solution

1 M in THF

• Synonym(s): N-Methylmethanamine boron complex, Lithium (dimethylamino)trihydroborate, Lithium trihydro(N-methylmethanaminato)borate
• Empirical Formula (Hill Notation): C₂H₉BLiN
• CAS Number: 53042-33-4
• Molecular Weight: 64.85
• MDL number: MFCD07784404
• UNSPSC Code: 12352000
• PubChem Substance ID: 24884338
• NACRES: NA.22

Properties

• reaction suitability: reagent type: reductant
• Quality Level: 100
• concentration: 1 M in THF
• refractive index: n20/D 1.423
• density: 0.882 g/mL at 25 °C
• storage temp.: 2-8°C
• SMILES string: [Li+].[BH3-]N(C)C
• InChI: 1S/C2H9BN.Li/c1-4(2)3;/h1-3H3;/q-1;+1
• InChI key: CEDUMRZWZLVFKS-UHFFFAOYSA-N

Description

General description

Lithium dimethylaminoborohydride is a reagent exhibiting dual properties like a metal hydride and nitrogen nucleophile. It is generally considered as an alternative to lithium aluminum hydride (LAH) for the reduction of carbonyl compounds, amides, and lactams.

Application

Lithium Aminoborohydride (LAB) Reagents

Reactant for:

• B-H oxidative addition reactions
• Reduction and amination reactions
• Reduction of N-alkyl lactams
• Synthesis of tertiary amine-boranes

Capable of reducing a variety of fuctional groups.

LABs can transfer the amine moiety, as in the case of the reaction with halopyridines and primary alkyl methanesulfonates.

Safety Information

• Pictograms: GHS02,GHS08,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H302,H319,H335,H351
• Precautionary Statements: P210 - P280 - P301 + P312 + P330 - P305 + P351 + P338 - P370 + P378 - P403 + P235
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• Target Organs: Respiratory system
• Supplementary Hazards: EUH019
• Storage Class Code: 4.3 - Hazardous materials which set free flammable gases upon contact with water
• WGK: WGK 3
• Flash Point(F): 1.4 °F - closed cup
• Flash Point(C): -17 °C - closed cup