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419702

Sigma-Aldrich

2-Mercaptopyridine-3-carboxylic acid

technical grade

Synonym(s):

2-Mercaptonicotinic acid

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About This Item

Empirical Formula (Hill Notation):
C6H5NO2S
CAS Number:
Molecular Weight:
155.17
Beilstein:
119029
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

grade

technical grade

form

powder

mp

263-265 °C (lit.)

functional group

carboxylic acid

SMILES string

OC(=O)c1cccnc1S

InChI

1S/C6H5NO2S/c8-6(9)4-2-1-3-7-5(4)10/h1-3H,(H,7,10)(H,8,9)

InChI key

WYKHFQKONWMWQM-UHFFFAOYSA-N

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Application

2-Mercaptopyridine-3-carboxylic acid may be used for the synthesis of poly[[diaquabis([μ]2-4,4 ′-bipyridyl)iron(II)] bis{2-[(3-carboxypyridin-2-yl)disulfanyl]nicotinate}] and 2-(2-carboxyethylthio)nicotinic acid.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Ioannis I Verginadis et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 42(3), 253-261 (2010-12-07)
Nowadays, investigation for possible therapeutic applications of various metal-based drugs attracts the scientific interest worldwide. The triorganotin compound bis[triphenyltin(IV)](3-carboxy-pyridine-2-thionato) (SnMNA), was tested for its anti-proliferative and antitumor activities. Cytotoxic activity was assessed by Trypan blue and 3-(4.5-dimethylthiazol-2-yl)-2.5-diphenyltetrazolium bromide assay (MTT).
Alexandra Partenhauser et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 105(3), 551-559 (2015-11-28)
Assessment of preactivated and thiolated silicone oils as potential long-term vitreous replacement. Thioglycolic acid (TGA) and 3-mercaptopropionic acid (MPA) were covalently coupled to amino-modified silicone oil and subsequently preactivated with 2-mercaptonicotinic acid (2-MNA). Each silicone thiomer was evaluated in view
Jie-Jie Shan et al.
Acta crystallographica. Section E, Structure reports online, 68(Pt 1), m28-m28 (2012-01-20)
In the title compound, {[Fe(C(10)H(8)N(2))(2)(H(2)O)(2)](C(12)H(7)N(2)O(4)S(2))(2)}(n), synthesized by hydro-thermal reaction, the 4,4'-bipyridyl ligands (one with symmetry 2, one with symmetry [Formula: see text]) connect Fe(2+) cations, forming a cationic layer parallel to (001). The coordination of the Fe(2+) cation (site symmetry
Sally L McArthur et al.
Langmuir : the ACS journal of surfaces and colloids, 20(9), 3704-3709 (2005-05-07)
One of the greatest challenges in mass spectrometry lies in the generation and detection of molecular ions that can be used to directly identify the protein from the molecular weight of the molecular ion. Typically, proteins are large (MW >
Javed Iqbal et al.
Biomaterials, 33(5), 1528-1535 (2011-11-29)
This study was aimed to synthesize polymeric excipients with improved mucoadhesive, cohesive and in situ-gelling properties to assure a prolonged retention time of dosage forms at a given target site, thereby achieving an increased uptake and improved oral bioavailability of

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