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109010

Sigma-Aldrich

3,3′-Dithiodipropionic acid

99%

Synonym(s):

2-Carboxyethyl disulfide, Bis(2-carboxyethyl) disulfide

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About This Item

Linear Formula:
HOCOCH2CH2SSCH2CH2COOH
CAS Number:
1119-62-6
Molecular Weight:
210.27
Beilstein:
1778543
EC Number:
214-284-0
MDL number:
MFCD00002780
UNSPSC Code:
12352100
PubChem Substance ID:
24846851
NACRES:
NA.22

Assay

99%

mp

155-158 °C (lit.)

SMILES string

OC(=O)CCSSCCC(O)=O

InChI

1S/C6H10O4S2/c7-5(8)1-3-11-12-4-2-6(9)10/h1-4H2,(H,7,8)(H,9,10)

InChI key

YCLSOMLVSHPPFV-UHFFFAOYSA-N

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General description

3,3′-Dithiodipropionic acid forms monolayers on a polycrystalline gold electrode through a self-assembly procedure to form gold 3,3′-dithiodipropionic acid self-assembled monolayer modified electrode. It is the precursor substrate in the synthesis of 3-mercaptopropionic acid-containing polythioesters. It is added as primary carbon supplement in the culture medium of novel betaproteobacterium, strain DPN7.

Application

3,3′-Dithiodipropionic acid was used as capping agent for introducing charge on gold nanoparticles surfaces.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Na Liu et al.
ACS applied materials & interfaces, 8(48), 33148-33156 (2016-12-10)
Redox-responsive nanomaterials applied in drug delivery systems (DDS) have attracted an increasing attention in pharmaceutical research as a carrier for antitumor therapy. However, there would be unwanted drug release from a redox-responsive DDS with no selection at nontarget sites, leading
Yanqin Xu et al.
Journal of biomaterials science. Polymer edition, 31(13), 1706-1721 (2020-07-03)
A pH and redox dual-responsive composite hydrogel was developed, which was formed from triblock copolymer PEG-SS-PCL-SS-PEG and Ag/AgO/carboxymethyl chitosan (CMCS) hydrogel inclusion complexes. Dithiodipropionic acid and poly(ethylene glycol) (PEG) were esterified to synthesize a hydrophilic segment PEG-SS-COOH polymer containing a
Taisuke Kojima
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 34(3), 363-368 (2018-03-13)
Molecular adsorption on a sensing surface involves molecule-substrate and molecule-molecule interactions. Combining optical systems and a quartz crystal microbalance (QCM) on the same sensing surface allows the quantification of such interactions and reveals the physicochemical properties of the adsorbed molecules.
Jan Hendrik Wübbeler et al.
International journal of systematic and evolutionary microbiology, 56(Pt 6), 1305-1310 (2006-06-02)
In this study, a novel betaproteobacterium, strain DPN7(T), was isolated under mesophilic conditions from compost because of its capacity to utilize the organic disulfide 3,3'-dithiodipropionic acid. Analysis of the 16S rRNA gene sequence of strain DPN7(T) revealed 98.5 % similarity
Tingting Meng et al.
International journal of pharmaceutics, 534(1-2), 368-377 (2017-10-21)
P-glycoprotein (P-gp) is a major efflux transporter overexpressed on multidrug resistant tumor cells and responsible for pumping drugs out. If anti-tumor drugs are given when P-gp level is low, satisfactory treatment efficiency may be achieved. Thus, a P-gp down-regulating siRNA
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