SMB00313

Gastrodin

≥98% (HPLC)

• Synonym(s): (2R,3S,4S,5R,6S)-2-Hydroxymethyl-6-(4-hydroxymethyl-phenoxy)-tetrahydro-pyran-3,4,5-triol, 4-β-D-glucopyranosyloxybenzyl alcohol, 4-Hydroxybenzyl alcohol 4-O-β-D-glucoside
• Empirical Formula (Hill Notation): C₁₃H₁₈O₇
• CAS Number: 62499-27-8
• Molecular Weight: 286.28
• MDL number: MFCD00272169
• UNSPSC Code: 12352205
• PubChem Substance ID: 329824945
• NACRES: NA.25

Properties

• biological source: plant (Gastrodia elata Blume)
• Assay: ≥98% (HPLC)
• form: powder
• application(s): detection; metabolomics; vitamins, nutraceuticals, and natural products
• storage temp.: 2-8°C
• SMILES string: O[C@@H]1[C@@H](CO)O[C@@H](OC2=CC=C(CO)C=C2)[C@H](O)[C@H]1O
• InChI: 1S/C13H18O7/c14-5-7-1-3-8(4-2-7)19-13-12(18)11(17)10(16)9(6-15)20-13/h1-4,9-18H,5-6H2/t9-,10-,11+,12-,13-/m1/s1
• InChI key: PUQSUZTXKPLAPR-UJPOAAIJSA-N

Description

General description

Gastrodin, a phenolic glucoside, is the main active ingredient of the traditional Chinese medicinal compound Tianma. Gastrodin is an active component of Gastrodia elata Blume, a herb belonging to the Orchidaceae family.

Application

Gastrodin has been used as a control to estimate the gastrodin content in the leaves, roots and stems of Anoectochilus formosanus Hayata.

Biochem/physiol Actions

Gastrodin can penetrate through the blood-brain barrier and has been suggested to have neuroprotective effects against hypoxia. It is also known to reduce the immunoreactivity of gamma-aminobutyric acid shunt enzymes in hippocampal tissues. Traditionally, gastrodin is also known to be effective in the treatment of headache, vertigo, dizziness and convulsive disorders. Along with anticonvulsant property, it also possesses antiepileptic, anxiolytic, anti-inflammatory and antiobesity action. Gastrodin is also helps in learning and memory stimulation.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302
• Precautionary Statements: P264 - P270 - P301 + P312 + P330 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable