G5793

GR 127935 hydrochloride hydrate

>98% (HPLC), powder

• Synonym(s): N-[4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2´-methyl-4´-(5-methyl-1,2,4-oxadiazol-3-yl)-1,1´-biphenyl-4-carboxamide hydrochloride hydrate
• Empirical Formula (Hill Notation): C₂₉H₃₁N₅O₃ · HCl · xH₂O
• CAS Number: 148642-42-6
• Molecular Weight: 534.05 (anhydrous basis)
• MDL number: MFCD11045922
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278688
• NACRES: NA.77

Properties

• Assay: >98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: 10 mg/mL, clear
• originator: GlaxoSmithKline
• storage temp.: 2-8°C
• SMILES string: O.Cl.COc1ccc(NC(=O)c2ccc(cc2)-c3ccc(cc3C)-c4noc(C)n4)cc1N5CCN(C)CC5
• InChI: 1S/C29H31N5O3.ClH.H2O/c1-19-17-23(28-30-20(2)37-32-28)9-11-25(19)21-5-7-22(8-6-21)29(35)31-24-10-12-27(36-4)26(18-24)34-15-13-33(3)14-16-34;;/h5-12,17-18H,13-16H2,1-4H3,(H,31,35);1H;1H2
• InChI key: KSXUSAQPMSACQS-UHFFFAOYSA-N
• Gene Information: human ... HTR1B(3351) , HTR1D(3352)

Description

Biochem/physiol Actions

Potent, selective and orally active 5-HT_1B/1D serotonin receptor antagonist.

Features and Benefits

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Caution

Desiccate

Legal Information

Sold for research purposes under agreement from Glaxo­Smith­Kline

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves