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F5130
5-Fluorouridine
5-Fluorouridine
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proapoptotic anitproliferative plant growth regulator
Synonym(s):
5-Fluorouracil 1β-D-ribofuranoside, FUrd
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About This Item
Empirical Formula (Hill Notation):
C9H11FN2O6
CAS Number:
Molecular Weight:
262.19
Beilstein:
33662
EC Number:
MDL number:
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.51
Pricing and availability is not currently available.
Recommended Products
biological source
synthetic (organic)
Quality Level
Assay
≥99% (HPLC)
form
powder
solubility
water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
SMILES string
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=C(F)C(=O)NC2=O
InChI
1S/C9H11FN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1
InChI key
FHIDNBAQOFJWCA-UAKXSSHOSA-N
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General description
Application
Biochem/physiol Actions
5-Fluorouridine (FUrd) is cytotoxic towards cancer cells.[1] FUrd is often used in chemical and biochemical comparison studies with fluorouracil and thymine analogs.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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The effects of 5-fluorouridine (FUrd) and 5-fluorodeoxyuridine (FdUrd) substitution on the stabilities of duplex RNA and DNA have been studied to determine how FUrd substitution in nucleic acids may alter the efficiency of biochemical processes that require complementary base pairing
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