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Sigma-Aldrich

Human Collagen Type I

SphereCol® coated beads

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.75

product name

SphereCol®, Human Collagen Type I Coated Beads, for 3D bio-scaffold

biological source

human

sterility

irradiated

form

liquid

packaging

pkg of 10 g

technique(s)

cell culture | mammalian: suitable

bead size

~125-212 μm

storage temp.

room temp

General description

SphereCol® human Type I collagen coated beads are ideal for growing cell in suspension. The collagen coated beads provide a natural in vivo-like environment to promote high cell growth while providing a large surface area for cells to attach with optimal surface area to volume ratios. SphereCol® provides a 3D bio-scaffold which is optimal in many cell culture procedures.

SphereCol®, human collagen coated beads are coated with highly purified Type I human collagen derived from a human fibroblast cell culture process, VitroCol. The collagen provides an optimal coating on the beads to enhance cell attachment, cell viability, cell proliferation and cell function. The collagen beads range in size from about 125 to 212 micron.

Application

SphereCol®, human collagen coated beads provide a surface area of 360cm2/gram of beads.

Legal Information

SphereCol is a registered trademark of Advanced BioMatrix, Inc.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Romel Dator et al.
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African American (AA) smokers are at a higher risk of developing lung cancer compared to whites. The variations in the metabolism of nicotine and tobacco-derived carcinogens in these groups were reported previously with the levels of nicotine metabolites and carcinogen-derived
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Journal of cellular physiology, 235(2), 932-943 (2019-06-27)
Histone demethylase KDM7A regulates neuronal differentiation and development in mammals. In this study, we found that KDM7A was also required for breast cancer stem cells (BCSCs) maintenance. Silencing KDM7A significantly reduced the BCSCs population and mamosphere formation in vitro, and
Liu Ying et al.
International journal of biological sciences, 16(12), 2180-2191 (2020-06-19)
The histone H3K9 methyltransferase SETDB2 is involved in cell cycle dysregulation in acute leukemia and has oncogenic roles in gastric cancer. In our study, we found that SETDB2 plays essential roles in breast cancer stem cell maintenance. Depleted SETDB2 significantly
Songjie Cai et al.
Scientific reports, 10(1), 14249-14249 (2020-08-30)
Solid organ transplantation is a lifesaving therapy for patients with end-organ disease. Current immunosuppression protocols are not designed to target antigen-specific alloimmunity and are uncapable of preventing chronic allograft injury. As myeloid-derived suppressor cells (MDSCs) are potent immunoregulatory cells, we
Xiaoyan Wen et al.
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Urinary tissue inhibitor of metalloproteinases (TIMP)-2 has been identified as a predictive marker for acute kidney injury (AKI), including sepsis-associated AKI (S-AKI). Whether TIMP-2 might be causally related to AKI and hence represent a viable drug target is unclear. The

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