33880

AOZ-d₄

VETRANAL^®, analytical standard

• Synonym(s): 3-Aminooxazolidin-2-one-d₄, 4,4,5,5-Tetradeutero-3-amino-oxazolidin-2-one
• Empirical Formula (Hill Notation): C₃H₂D₄N₂O₂
• CAS Number: 1188331-23-8
• Molecular Weight: 106.12
• MDL number: MFCD06201845
• UNSPSC Code: 41116107
• PubChem Substance ID: 329754688
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• product line: VETRANAL^®
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): clinical testing
• format: neat
• mass shift: M+4
• SMILES string: [2H]C1([2H])OC(=O)N(N)C1([2H])[2H]
• InChI: 1S/C3H6N2O2/c4-5-1-2-7-3(5)6/h1-2,4H2/i1D2,2D2
• InChI key: KYCJNIUHWNJNCT-LNLMKGTHSA-N

Description

General description

It is an isotopically labelled solution of AOZ, also known as 3-amino-2-oxazolidinone, a metabolite of the synthetic nitrofuran veterinary antibiotic― furazolidone.

Application

The analytical standard can be used as an internal standard for the following:

• Multi-residue analysis of four nitrofuran metabolites residues in 120 fish samples by ultra high-performance liquid chromatography (UHPLC) combined with tandem mass spectrometry (MS/MS)
• Determination of four nitrofuran metabolites in a variety of food samples by liquid chromatography-tandem mass spectrometry (LC-MS/MS) following their extraction using a solid-phase microextraction (SPME) probe
• Simultaneous estimation of nitrofuran and chloramphenicol residues in animal-based food products using UHPLC, coupled with high-resolution mass spectrometry (HRMS)
• Development of a UHPLC-MS/MS-based method for the estimation of nitrofurans along with their metabolites in biological samples
• Liquid-liquid extraction of chloramphenicol, florfenicol, and nitrofuran metabolites from honey samples for their analysis by LC-MS/MS
• Estimation of nitrofuran metabolites in poultry muscle and eggs using liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS).

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves