8.08260
Trifluoroacetic acid
for synthesis
Synonym(s):
TFA
About This Item
Recommended Products
vapor density
3.9 (vs air)
Quality Level
vapor pressure
97.5 mmHg ( 20 °C)
Assay
≥99% (acidimetric)
form
liquid
refractive index
n20/D 1.3 (lit.)
pH
1 (10 g/L in H2O)
bp
72.4 °C (lit.)
mp
−15.4 °C (lit.)
solubility
soluble 10 g/mL
density
1.489 g/mL at 20 °C (lit.)
storage temp.
2-30°C
SMILES string
OC(C(F)(F)F)=O
InChI
1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)
InChI key
DTQVDTLACAAQTR-UHFFFAOYSA-N
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Related Categories
General description
Application
- In the direct conversion of cyclohexanone to caprolactam using acetonitrile as the additive.
- In the synthesis of 1,2,4,5-tetrasubstituted imidazoles by four-component condensation of benzil, aldehydes, amines, and ammonium acetate.
- In the synthesis of d-α-Tterpineo from d-limonene by Markovnikov addition followed by hydrolysis.
Features and Benefits
- High acidity
- Easy elimination
- Good solubility in organic solvent and in water.
Analysis Note
Density (d 20 °C/ 4 °C): 1.487 - 1.490
Identity (IR): passes test
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A
Storage Class Code
8A - Combustible corrosive hazardous materials
WGK
WGK 2
Flash Point(F)
>212.0 °F - Pensky-Martens closed cup
Flash Point(C)
> 100 °C - Pensky-Martens closed cup
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Protocols
Fmoc resin cleavage and deprotection are crucial steps for peptide synthesis, yielding the desired peptide after resin detachment.
Fmoc resin cleavage and deprotection are crucial steps for peptide synthesis, yielding the desired peptide after resin detachment.
Fmoc resin cleavage and deprotection are crucial steps for peptide synthesis, yielding the desired peptide after resin detachment.
Fmoc resin cleavage and deprotection are crucial steps for peptide synthesis, yielding the desired peptide after resin detachment.
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