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M-019

Supelco

(±)-Methadone solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C21H27NO
CAS Number:
76-99-3
Molecular Weight:
309.45
EC Number:
200-659-6
MDL number:
MFCD00056289
UNSPSC Code:
41116107
PubChem Substance ID:
329817736

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

concentration

100 μg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

−20°C

SMILES string

CCC(C(CC(C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2)=O

InChI

1S/C21H27NO/c1-5-20(23)21(16-17(2)22(3)4,18-12-8-6-9-13-18)19-14-10-7-11-15-19/h6-15,17H,5,16H2,1-4H3

InChI key

USSIQXCVUWKGNF-UHFFFAOYSA-N

Gene Information

human ... OPRM1(4988)

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General description

Methadone is a synthetic opioid used medically as an analgesic and as a maintenance anti-addictive for use in patients with opioid dependency. The drug is sold under several trade names such as Symoron, Dolophine®, Amidone, Methadose®, Physeptone, or Heptadon. This Certified Spiking Solution® is suitable for LC/MS or GC/MS testing methods in pain prescription monitoring, forensic analysis or clinical toxicology.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Dolophine is a registered trademark of Roxane Laboratories, Inc.
Methadose is a registered trademark of Mallinckrodt Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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(±)-Methadone solution, 1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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E-006

EDDP perchlorate, ampule of 10 mg, certified reference material, Cerilliant®

E-021

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E-022

EDDP perchlorate solution, 1.0 mg/mL in methanol (as pyrolinium), ampule of 1 mL, certified reference material, Cerilliant®

E-057

EMDP hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

E-062

EDDP-D3 perchlorate solution, 1.0 mg/mL in methanol (as pyrrolinium), ampule of 1 mL, certified reference material, Cerilliant®

M-008

(±)-Methadone-D3 solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

M-021

(±)-Methadone-D3 solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

M-088

(±)-Methadone-D9 solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

M-089

(±)-Methadone-D9 solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Kobra Lashkaripour et al.
JPMA. The Journal of the Pakistan Medical Association, 62(10), 1003-1007 (2013-07-23)
To examine the 3-month effect of methadone maintenance treatment (MMT) on quality of life (QOL) of substance-dependent outpatients in Iran. The qausi-experimental study performed at the Oral Maintenance Methadone Treatment Clinic of the Baharan Psychiatric Hospital, a university hospital in
The lethal burden of drug overdose.
Lancet (London, England), 382(9895), 833-833 (2013-09-10)
David Kao et al.
Annals of internal medicine, 158(10), 735-740 (2013-05-22)
Long-acting opioids are a leading cause of accidental death in the United States, and methadone is associated with greater mortality rates. Whether this increase is related to the proarrhythmic properties of methadone is unclear. To describe methadone-associated arrhythmia events reported
Advice on methadone and oral health: dental public health in action.
C M Jones et al.
Community dental health, 30(2), 68-70 (2013-07-31)
Philippa Hawley et al.
Pain research & management, 18(2), 83-86 (2013-05-11)
Methadone is one of the most important medications used for the treatment of refractory pain in the palliative care setting, and is usually initially prescribed by one of a limited number of physicians who have acquired authorization for its use.
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