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P31701

Sigma-Aldrich

2-Phenylpropionic acid

97%

Synonym(s):

(±)-2-Phenylpropionic acid, (±)-Hydratropic acid

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About This Item

Linear Formula:
CH3CH(C6H5)CO2H
CAS Number:
492-37-5
Molecular Weight:
150.17
Beilstein:
1863558
EC Number:
207-752-0
MDL number:
MFCD00002650
UNSPSC Code:
12352100
PubChem Substance ID:
24898400
NACRES:
NA.22

Assay

97%

refractive index

n20/D 1.522 (lit.)

bp

260-262 °C (lit.)

density

1.1 g/mL at 25 °C (lit.)

SMILES string

CC(C(O)=O)c1ccccc1

InChI

1S/C9H10O2/c1-7(9(10)11)8-5-3-2-4-6-8/h2-7H,1H3,(H,10,11)

InChI key

YPGCWEMNNLXISK-UHFFFAOYSA-N

Gene Information

human ... IL8RA(3577)

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Related Categories

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

298.4 °F

Flash Point(C)

148 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Lina Sagert et al.
eLife, 9 (2020-03-14)
Adaptive immunity vitally depends on major histocompatibility complex class I (MHC I) molecules loaded with peptides. Selective loading of peptides onto MHC I, referred to as peptide editing, is catalyzed by tapasin and the tapasin-related TAPBPR. An important catalytic role
Y Nakamura et al.
Drug metabolism and disposition: the biological fate of chemicals, 15(4), 529-534 (1987-07-01)
Optical isomerization of 2-phenylpropionic acid (hydratropic acid, HTA) was studied in the organs of male rat in vitro. (R)-(-)-HTA was not isomerized by rat liver homogenate even after the addition of CoA, ATP, and Mg2+ to the incubation mixture; however
Chunze Li et al.
The Journal of pharmacology and experimental therapeutics, 305(1), 250-256 (2003-03-22)
Two alternative metabolic pathways, acyl glucuronidation and acyl-CoA formation, are implicated in the generation of reactive acylating metabolites of carboxylic acids. Here, we describe studies that determine the relative importance of these two pathways in the metabolic activation of a
Chunze Li et al.
Chemical research in toxicology, 15(11), 1480-1487 (2002-11-20)
A series of studies was conducted to investigate the potential of (R)- and (S)-2-phenylpropionic acid (2-PPA) to undergo enantioselective covalent binding to protein in freshly isolated rat hepatocytes and to determine whether such covalent binding is dependent on acyl glucuronidation
Shengqiang Tong et al.
Journal of chromatography. A, 1281, 79-86 (2013-02-20)
High performance liquid chromatography (HPLC) and high speed counter-current chromatography (HSCCC) were applied and compared in enantioseparation of 2-phenylpropionic acid (2-PPA) when hydroxypropyl-β-cyclodextrin (HP-β-CD) was used as chiral mobile phase additive. For HPLC, the enantioseparation was achieved on ODS C(18)
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