Skip to Content
Merck
All Photos(1)

Key Documents

630721

Sigma-Aldrich

6-Aminoindole

97%

Synonym(s):

Indol-6-ylamine, NSC 82379

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C8H8N2
CAS Number:
Molecular Weight:
132.16
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

97%

form

solid

mp

75-79 °C

storage temp.

−20°C

SMILES string

Nc1ccc2cc[nH]c2c1

InChI

1S/C8H8N2/c9-7-2-1-6-3-4-10-8(6)5-7/h1-5,10H,9H2

InChI key

MIMYTSWNVBMNRH-UHFFFAOYSA-N

Application

Reactant for preparation of:
  • Inhibitors of mammalian target of rapamycin (mTOR ) protein
  • Inhibitors of the AcrAB-TolC efflux pump
  • Inhibitors of Gli1-mediated transcription in the Hedgehog pathway
  • Potent DNA-topoisomerase II poisons and anti-MDR agents
  • Protein kinase C θ (PKCθ) inhibitors
  • Piperidine carboxamide as transient receptor potential cation channel subfamily V member 1 (TRPV1) antagonists
  • Potent and selective blockers of the Nav1.8 sodium channel as potential analgesics for the treatment of neuropathic and inflammatory pain
  • 5,6-fused heteroaromatic ureas as TRPV1 antagonists
  • Allosteric enhancers of the A3 adenosine receptor
  • Human liver glycogen phosphorylase (HLGP) inhibitors for the treatment of type 2 diabetes

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service